Factory Customized Oxidation fermentation stainless steel automatic Bioreactor

Process types
Microbial fermentation,antibiotic fermentation,nucleic acid fermentation,enzyme fermentation,yeast fermentation,starter fermentation.

Fermentation types
Oxidation fermentation,facultative fermentation,anaerobic fermentation.

Material types
Liquid state fermentation,semi-liquid state fermentation,solid fermentation.

Coefficient of charge
70~75%

Ventilation ratio
1~2vvm

Height-diameter ratio
2~2.5

Culture medium sterilizing type
Actual sterilization,continuous sterilization,UHT continuous sterilization,etc.

Culture types
fungus,bacterium,actinomyces.

Culture expanding types
Single tank fermentation;multi-stage fermentation,disk-type fermentation.


Tank series
10L,20L,30L,50L,100L,200L,300L,500L,1m³,2m³,3m³,5m³,10m³,20m³,30m³,50m³,80m³,100m³,customized.

• Fermentation tank structure features:

(1) Design standard:Based on the ASME clean equipment standard to design and manufacture;complying with the requirements of Pressure Vessel at the same time;

(2)Inner surface treatment
Mechanical polishing Ra‹0.4μm,and then performing the mirror process;

(3)Outer surface treatment
Mechanical polishing Ra‹0.6μm,and then performing the matting process;

(4)No blind coner treatment
The inner welding line and the inner surface being polished,and structure components adopting the full length welding,and then polishing,inner coil pipe using the stress eliminating structure;

(5)Fastener structure
All fasteners using the bolt stud balancing double acorn nuts,PTFE materia as gasket seal;

(6)Mechanical seal
Using the washable,sterilized collection plate equipped mechanical seal fixed and moving ring friction sleeve to ensure the friction debris not falling into the tank;
sealed pattern:dry or wet type,single end face or dual end face;

(7)Heat exchange type
Full Jacket,dimple jacket,semicircle-pipe jacket,inner coil,inner tubulation;

• Piping system features:
(1) Processing piping
Adopting ASME sanitary grade internal and external polished cleanig pipe.It is weld automatically with argon gas,inspected by endoscope.

(2)Valves
The valves connected with tanks all adopting double membrane combination
diaphragm valve;all steam and compressed air valve are both using stop valves and sanitary ball valves.

(3)Double membrane diaphragm type tank bottom valve ,sterilizing at the product outlet before sampling;

(4)Online sterilization
Adopting the clean and saturated steam filtered by 0.5μm titanium rod filter;

(5)Sampling method
Adopting the diaphragm type aseptic sampling valve,doing online sterilization before sampling and take aseptic sample;

(6)Subcultivation
The pipe can be sterilized during the whole progress,installing the thermometer to sterilization detection;

(7)Inoculation method
Flame ring type,different pressure type;

(8)Feeding mode
Peristaltic pump,measuring cup,etc.

(9)Multi-stage culture expanding system subcultivation
Subcultivation distributor to do the multitubes distribution subcultivation valve manifolds subcultivation,etc.