Dmpat-Spermine Crystalline Solid Organophosphorus Pesticide Intermediate
2,3-Difluoro-5-Chloropyridine For The Synthesis Of High-Efficiency Pesticide Clodinafop-Propargyl Cas 89402-43-7
DESCRIPTION
Spermine, putrescine, and spermidine form the polyamine family (polycation), which is essential for the growth and survival of the vast majority of living cells. Polyamines interact with negatively charged molecules, such as proteoglycans, glycated proteins, and nucleic acids (DNA and RNA). Biological polyamines have been found to regulate protein synthesis at different levels. This effect can be explained as polyamine binding and affecting the secondary structure of tRNA, mRNA, and rRNA. Spermine also helps to stabilize the nucleic acid helix structure and form glycosylated proteins such as histones. Spermine and spermidine are components of various nucleic acid transfection schemes.
Specification
| product Name | DMPAT |
| Synonyms | O,O-dimethylamidothiophosphate; O,O-Dimethyl Phosphoroamido Thioate; N,N-Bis(3-aminopropyl)-1,4-butanediamine; Spermine; N,N-Bis(3-aminopropyl)-1,4-diaminobutane; 4,9-diazadodecamethylenediamine; Spermine dihydrate; N,N-Bis(3-aminopropyl)-1,4-diaminobutane; Gerontine; Musculamine; Neuridine; N,N'-bis(3-aminopropyl)butane-1,4-diamine; O,O-dimethyl phosphoramidothioate; N,N'-bis(3-ammoniopropyl)butane-1,4-diaminium; O,O-Dimethyl thiophosphoramidate |
| Molecular Formula | C10H26N4 |
| Molecular Weight | 202.3698 |
| InChI | InChI=1/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2/p+4 |
| CAS Registry Number | 71-44-3;17321-47-0 |
| EINECS | 200-754-2 |
| Molecular Structure |
71-44-3;17321-47-0 DMPAT |
| Melting point | 26-30℃ |
| Boiling point | 308.4°C at 760 mmHg |
| Flash point | 175.6°C |
| Vapour Pressur | 0.000683mmHg at 25°C |
| Hazard Symbols | C:Corrosive; |
| Risk Codes | R34:; |
| Safety Description | S26:; S36/37/39:; S45:; |
USES
Agonists/antagonists of mixed NMDA glutamate receptors at polyamine sites. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity can be observed at low concentrations. It enhances the reaction at the glycine site that is not sensitive to brucine. Plays a major role in cell proliferation and differentiation; Inhibition of neuronal nitric oxide synthase (nNOS).
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