NHS Magnetic Polymer Beads Preactivated N-Hydroxy Succinimide Nanoparticle 2 μm with 50 μM/mL Ligand Content

Price Negotiable

Price: Negotiation

MOQ: 1 mL / bottle

Delivery Time: 5-8 days

Brand: BeaverBeads

Product Description

Product Overview

BeaverBeads™ Mag NHS and BeaverBeads™ Magrose NHS are spherical magnetic polymer beads preactivated with N-Hydroxy Succinimide (NHS) groups. These 2 μm nanoparticles enable direct covalent coupling with proteins and other molecules containing primary amine groups for affinity purification and assay detection applications.

Technical Specifications

Parameter	Specification
Mean Particle Size	2 μm
Magnetic Core	Fe3O4
Shell Material	Polymer
Magnetic Properties	Superparamagnetic
Ligand Content	~50 μM/mL gel
Binding Capacity	20-30 mg rabbit IgG/mL beads
Preservation Fluid	DMAC
Operation Mode	Automated/Manual

Key Features

Simple operation - No activation required, direct covalent coupling with biological ligands
High efficiency - Up to 90% bio-ligand coupling efficiency with enhanced binding capacity
Rapid processing - Complete bio-ligand coupling in 1-2 hours
Mild conditions - Room temperature or 4°C coupling with pH range 5-9
Stable bonding - Forms stable amide bonds to prevent ligand detachment
Excellent biocompatibility - Reduced nonspecific adsorption for cleaner results

Handling & Storage Guidelines

Important Precautions

Magnetic beads are sensitive to moisture - Immediately reseal containers after sampling and store at 4°C
Avoid drying or freezing - These conditions may cause bead aggregation and loss of binding activity
Protein content determination - Use indirect methods (e.g., Thermo Scientific™ Pierce™ 660 nm Protein Assay) or direct methods (e.g., Micro BCA Protein Assay)
Avoid 280 nm wavelength detection - NHS groups strongly absorb near 280nm and interfere with measurements