Acquired immunodeficiency syndrome (AIDS) is caused by either HIV-1 or HIV-2 or by both. They are mainly transmitted by unprotected contact, exposure to infected blood through a syringe, needle, and blood transfusion or from mother to fetus and through breast feeding. Belonging to the retrovirus class, both HIV1 and HIV 2 share many similarities including their basic gene arrangement, modes of transmission, intracellular replication pathways and clinical consequences: both result in AIDS.

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