Allergen Testing Immunoglobulin E(IgE) test kit for Clinical In Vitro Diagnostic analyzer

^{Immunoglobulin E}

^{(IgE) has a high affinity for basophils and mast cells, so it is also called reagin or cytophilic antibody. IgE is mainly produced by the plasma cells of the lamina propria of the respiratory tract and digestive tract mucosa, and its content is extremely low in the blood of normal people, accounting for about 0.002% of the total serum Ig. IgE is related to type I allergy. In patients with allergic constitution or hypersensitivity, the serum IgE is significantly higher than that of normal people, so the high level of IgE in serum often indicates the existence of genetic allergy or type I allergy.}

^{Clinical significance}

^{Detection of the content of immune globulin in the body can understand the state of the body's humoral immune function and help diagnose various diseases such as immune hyperplasia, immune deficiency, infection and autoimmunity, which has important clinical significance.}

^{1. Elevated serum IgE: common in hypersensitivity diseases such as allergic rhinitis, extrinsic asthma, hay fever, chronic urticaria, as well as parasitic infection, acute and chronic hepatitis, drug-induced interstitial pneumonia, bronchial Pulmonary aspergillosis, eczema, rheumatoid arthritis and IgE multiple myeloma, etc.}

^{2. Decreased serum IgE: seen in primary agammaglobulinemia, after the application of tumor and chemotherapy drugs, ataxia-telangiectasia, etc.}

^{Normal value reference range}

^{Normal reference value of serum IgE content: <100IU/ml.}

CLIA Reagents of Allergen(IgE)