Homoharringtonine/Cephalotaxus Fortunei Extract/Homoharringtonine 98% Powder 26833-87-4

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Homoharringtonine/Cephalotaxus Fortunei Extract/Homoharringtonine 98% Powder 26833-87-4

homoharringtonine

Other name: Cephalotaxine 4-methyl 2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate
Botanical source: Cephalotaxus fortunei
Extracted part: leaf
Assayed by HPLC: 98%homoharringtonine
Cas Number : 26833-87-4
Molecular formula : C29H39O9
M.W. : 545.6284
Appearance:White or light yellow powder

What is Homoharringtonine?
Separated from our Cephalotaxus one anti-tumor plant alkaloids, is a cell cycle-specific drugs, G1 and G2 phase of the cell killing effect of the strongest, while a smaller effect on cells in S phase. HHPT major inhibition of protein synthesis in eukaryotic cells, combined inhibition of the formation of aminoacyl -tRNA ribosomes and ribosomal peptide chain, thus the impact of an early stage before the polymer is formed, and polysome depolymerization off, interfere with protein function of ribosomes, the cell DNA synthesis is also inhibited. This product is to promote the process of degeneration and necrosis of the nucleus and tri HARRINGTONINE same. HHRT can promote cell differentiation and apoptosis.

Function:

1.Alkaloid from Cephalotaxus hainanensis.

2.To possess anti-leukemic activity