1,1,3,3-Tetramethylguanidine As A Nonaqueous Solvent Cas 80-70-6
1,1,3,3-Tetramethylguanidine As A Nonaqueous Solvent Cas 80-70-6
DESCRIPTION
Tetramethylguanidine is an organic compound with the formula HNC(N(CH3)2)2. This colourless liquid is a strong base, as judged by the high pKa of it conjugate acid.It was originally prepared from tetramethylthiourea via S-methylation and amination, but alternative methods start from cyanogen iodide.
Specification
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CAS No.
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80-70-6
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|
MF
|
C5H13N3
|
|
EINECS No.
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201-302-7
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|
Place of Origin
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China
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Density
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0.9g/cm3
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Water solubility
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miscible
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|
Refractive index
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1.445 |
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Flash point
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60°C
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|
Vapour Pressure
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2.09mmHg at 25°C
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|
Appearance
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Liquid
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|
Mp
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-30℃
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|
Bp
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163.2°C at 760 mmHg
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|
Molecular Weight
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115.1768
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Sample
|
Availiable
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|
Safety Description
|
S16:;
S26:;
S36/37/39:;
S45:;
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| Risk Codes | R10:; R20/22:; R34:; |
USES
Tetramethylguanidine is mainly used as a strong, non-nucleophilic base for alkylations, often as a substitute for the more expensive DBU and DBN. Since it is highly water-soluble, it is easily removed from mixtures in organic solvents. It is also used as a base-catalyst in the production of polyurethane.
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