8 Minutes SARS CoV 2 Covid 19 Rapid Test Kit For Neutralizing Antibody

Result Within 8 Minutes for SARS-CoV-2 Neutralizing Antibody Rapid Test Kit ​

When someone contracts COVID-19, the host’s immune response can be measured by the presence of neutralizing antibodies. Neutralizing antibodies prevent the interaction between the SARS-CoV-2 virus and receptors on human cells, giving the patient immunity.

Neutralizing antibody detection is therefore very important in understanding and treating COVID-19. For example, to:

1. Test neutralizing antibody induction during vaccine development, and how long antibodies are present for after infection
2. Confirm COVID-19 patient immunity
3. Allow donor selection in convalescent plasma therapy (using the antibodies of immune patients to help patients with active COVID-19)
4. Identify compounds that can interfere with the mechanism of viral infection, to prevent or treat COVID-19

Neutralizing antibody detection kits work on the ELISA principle, normally, the reaction between Horseradish peroxidase (HRP) and colorimetric substrate. To detect Neutralising antibodies, either ACE2 or RBD is labeled with HRP, and the other is bound to a plate. In the example below, ACE2 is labeled.

If the donor sample contains neutralizing antibodies, RBD and ACE2 will not bind together. ACE2 will be washed off, and there will be no signal

If there are no neutralizing antibodies, RBD and ACE2 will bind and ACE2 will not be washed off. The HRP on ACE2 will then be able to react with the colorimetric substrate, producing a signal.

Result interpretation