This study is a randomized, controlled, single-blind, single-arm, interventional clinical study.

Randomization: This study uses SPSS to generate random numbers by a person who does not have contact with the patients before the experiment, and the patients are grouped according to the generated numbers.

Experimental grouping: Thisstudy is divided into 2 groups. In experimental group 1,materials with a fluoride content of 2 2600 ppm are used for tooth surface treatment before radiotherapy. 2 2600 ppm materials were treated with tooth surface treatment once; experimental group and control group were not treated with tooth surface treatment with materials with fluoride content of 2 2600 ppm ; before radiotherapy and at 1, 3, 6, 9, and 12 months after radiotherapy , The OHIP-14 scale was used to collect the oral problems of the patients. At the same time, the oral health education was conducted by the stomatologist to observe the oral cavity of the patients, and to collect the other oral damages of the patients.

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