Immunoassay test kit Serum assay kit CHI3L1 for Automatic immunoassay analyzer in Hepatic Fibrosis

Chitinase 3-like protein 1 (Chitinase 3-like protein 1, CHI3L1) is a monomeric glycosylated protein containing 383 amino acids and a molecular weight of 42.6KD. It is a member of the glycosyl hydrolase family. one. It can bind chitin but has no chitinase activity. Plays an important role in inflammation and tissue remodeling.

Serum CHI3L1 levels are elevated in patients with alcoholic cirrhosis, and CHI3L1 protein in blood is associated with chronic hepatitis C virus infection and liver fibrosis. Studies have found that in the serum of patients with liver cirrhosis, the concentration of CHI3L1 can be significantly increased. It is enriched and specifically expressed in the liver as a high-sensitivity and high-specificity serum detection marker for liver fibrosis staging and diagnosis.

Scope of application:
Liver fibrosis and liver cirrhosis caused by various causes of liver injury, including viral, alcoholic, drug-related, autoimmune, toxic, genetic and metabolic, etc.
Grading Basis for Severity of Liver Fibrosis and Cirrhosis
Dynamic monitoring of liver fibrosis after etiological treatment (such as antiviral therapy, antifibrotic therapy, etc.)
Health Checkup: Screening for Liver Fibrosis and Cirrhosis
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