0.45 μM PES Membranes Unsupported Film For Making PES Cartridge Filters

The Lenge PES membranes are highly asymmetric with a distinct uniform integral retention layer. The membranes have a high surface porosity and gradually increased pore size distribution in the direction facing upstream of filtration. Therefore, the membranes have a capability of retaining various sized particulates and biological species. The Lenge PES membrane filters have the following distinguished characteristics:

· High flux

· High capacity

· High porosity

· Low leaching
 

The validation of bacterial B. diminuta retention for 0.22 µm rated pharmaceutical grade cartridges was performed in accordance with American Society of Testing and Materials (ASTM) method F838-05. Using this test methodology, 0.22 µm rated pharmaceutical grade filters retained greater than 1 x 10⁷ CFU of B. diminuta per cm² of effective filter surface area.

Features and Benefits
 

• Complies with United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88> for biosafety, cytotoxicity, and hemolysis testing.
• The optimized built-in Highly asymmetric prefilter layer for maximum flow and throughput performance.
• Compatible with EtO, gamma irradiation, and SIP/autoclave methods of sterilization.

Sealing methods
 

• Mechanical
• Heat
• Ultrasonic
• RF welding
• Insert molding

LENGE Membrane VS Some Other Brand Membrane
 

SEM micrograph for Surface of PES Microporous Membrane (0.22 µm)
 

LENGE Membrane Some Brand Membrane
 

Shown at 5000X magnification

Comments: LENGE Membrane Has More and Smaller Microporous Than Some Brand Membrane.

Dirt Holding Capacity Test - 0.22 µm PES Membrane by PVP

Test by Fermentation Broth

Dirt Holding Capacity Test - 0.22 µm PES Membrane by Fermentation Broth

Comments: 3M Vmax= 2500 L/m2; LENGE Vmax= 10000 L/m2

Test By 2.5% Bovine Serum

Dirt Holding Capacity Test - 0.22 µm PES Membrane by 2.5% Bovine Serum

Comments: 3M Vmax= 143 L/m2; LENGE Vmax= 204 L/m2

Bubble Point Consistency - 0.22 µm PES filter cartridges