How to Choose a Biosafety Cabinet for Cleanrooms‌

When selecting a biosafety cabinet for cleanroom environments, it is essential to consider key factors such as protection level, airflow parameters, filtration efficiency, and compliance with certifications. Below are the core selection criteria and product recommendations.

‌1. Key Performance Indicators‌

• ‌Airflow Velocity‌
  • ‌Inflow Airflow‌: Protects the operator. For Class II biosafety cabinets, it should be ≥0.5 m/s (e.g., 0.53 m/s or 0.55 m/s) to prevent aerosol leakage.
  • ‌Downward Airflow‌: Protects the sample, typically ≥0.25 m/s (e.g., 0.35 m/s) to ensure stable vertical laminar flow.
• ‌Filtration Efficiency‌
  • HEPA filters must capture ≥99.995% of 0.3 μm particles (e.g., 99.9995% or 99.999%) to block pathogens.
• ‌Certifications & Compliance‌
  • Must have medical device registration and meet standards like YY0569-2011 (China) or NSF/ANSI 49 (International).

‌2. Application Scenarios & Safety Levels‌

• ‌Class II Biosafety Cabinets‌: Suitable for BSL-2 operations (e.g., clinical testing, cell culture), protecting personnel, samples, and the environment.
• ‌Class III Biosafety Cabinets‌: Designed for BSL-3/4 high-risk pathogens (e.g., Ebola virus), featuring fully enclosed design and dual HEPA filtration.