PO Nanofiber Membrane Chromatography Syringe designed for capture of plasmids and plasma components with 33mm diameter and 0.45μm pore size. This cation ion exchange chromatography system is engineered for pharmaceutical industry applications requiring high-performance separation and purification.

Ion exchange chromatography separates compounds based on net charge using media with charged functional groups covalently bound to a solid support. Cation exchangers contain positively charged groups that adsorb and retain negatively charged compounds, while neutral or similarly charged compounds pass through. Bound compounds are reversibly eluted using salt or pH gradients.

• Capture of large particles including recombinant proteins, plasmids, viruses, viral vectors, and plasma components
• Polishing steps to remove contaminants such as host DNA, HCPs, and endotoxins in biological fluids
• Fine purification of small molecule drugs including oligonucleotides and peptides

• Materials compatible with both aqueous and mild organic solutions
• 100% passed integrity testing for reliable performance
• Low-binding membrane minimizes sample loss
• Low IC extractables ensure sample purity
• Ethylene oxide or gamma irradiation sterilization options
• Ready-to-use equipment with easy connection to syringe filters or pumps
• High adsorption capacity for macromolecules
• High flow rate and separation capacity
• Well-developed separation functionality