CAS 113274-56-9 Leech Extract 300-1200 ATU/G Hirudin Powder
Hirudin Powder
What is Hirudin Powder?
Hirudin is the most active and extensively studied component among the various active ingredients extracted from leeches and their salivary glands. It is a small polypeptide composed of 65-66 amino acids. Leeches are rich in hirudin, which has a very strong inhibitory effect on thrombin, making it the strongest natural specific inhibitor of thrombin discovered to date. Hirudin possesses strong anticoagulant and antithrombotic effects, and has broad application prospects in the clinical treatment and prevention of various types of thrombosis.
Feature
Potential and Specific Inhibition of Thrombin:Thrombin is the "central processor" in the coagulation process, catalyzing the conversion of fibrinogen into fibrin, forming a network of thrombi. Hirudin binds irreversibly to thrombin at a 1:1 ratio with extremely high affinity, directly and thoroughly inhibiting its activity and preventing fibrin formation at its source.
Anti-Platelet Aggregation: Thrombin itself is a powerful platelet activator. By inhibiting thrombin, hirudin can also indirectly prevent platelet aggregation and activation, thus doubly blocking thrombus formation.
Unblocking Blood Vessels and Improving Microcirculation:Through highly effective anticoagulation, it reduces blood viscosity, dissolves existing microthrombi, and thus improves systemic blood flow and microcirculation.
Applications
Cardiovascular and Cerebrovascular Diseases: Used as an adjunct treatment for conditions such as angina pectoris and cerebral infarction, improving blood flow by reducing the risk of thrombosis.
Postoperative Care: Prevents deep vein thrombosis after surgical procedures (such as joint replacement and vascular surgery).
Trauma and Microcirculatory Disorders: Topical preparations can reduce swelling after soft tissue injury; oral or injectable medications help improve ischemic organ lesions.
Product Parameters
| Items | Standards | Results |
| Physical and chemical analysis: | ||
| Description | Dark brownish red powder (varies with season) | Complies |
| smell | Special fishy smell | Complies |
| Assay | ≥300ATU/g | 331 |
| mesh size | 90% pass80 mesh | Complies |
| Ash Content | ≤8% | 4.53% |
| Moisture | ≤8% | 4.27% |
| Residue analysis: | ||
| lead | 10mg/kg | Complies |
| PH | 5-7.5 | Complies |
| As | 5mg/kg | Complies |
| Hg | 1mg/kg | Complies |
| Cd | 1mg/kg | Complies |
| Microbiological: | ||
| Total Plate Count | ≤1000cfu/g | Complies |
| Yeast&Mold | ≤100cfu/g | Complies |
| E.coil | Negative | Negative |
| Salmonella | Negative | Negative |
| General Status: | ||
| GMO Free | Complies | Complies |
| Non-Irradiation | Complies | Complies |
For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin
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