Pre-Compression 8 Station Laboratory Rotary Tablet Press Machine 80KN For Pharmaceutical Formulation Development
Purpose-built for pharmaceutical formulation scientists and R&D teams, this 8 station rotary tablet press features an integrated pre-compression system that mimics production-scale compression behavior. The dual-stage compression process de-aerates the powder before final compaction, delivering tablet properties that reliably predict scale-up performance. Ideal for powder characterization, formulation screening, and clinical trial material production.
| Parameter | TEU-8 |
|---|---|
| Dies (sets) | 8 |
| Punch Type | EUD |
| Max. Pressure (KN) | 80 |
| Max. Pre-Pressure (KN) | 10 |
| Max. Tablet Diameter - Round (mm) | 20 |
| Max. Tablet Length - Shaped (mm) | 23 |
| Max. Filling Depth (mm) | 17 |
| Max. Tablet Thickness (mm) | 6 |
| Max. Turret Speed (r/min) | 5-30 |
| Capacity (pcs/hour) | 14,400 |
| Motor Power (KW) | 2.2 |
| Overall Dimensions (mm) | 750 x 660 x 1,620 |
| Net Weight (kg) | 780 |
- Independent pre-compression and main compression stages with individually adjustable force settings (0-10KN pre / 0-80KN main)
- Dual-stage compression simulates production tablet press behavior, providing reliable compressibility and compaction data for scale-up prediction
- Adjustable turret speed (5-30 r/min) allows systematic dwell time sensitivity studies for formulation optimization
- Precision fill cam with 17mm maximum depth accommodates low-density powders and granulated formulations
- EUD punch tooling compatible with standard rotary press tooling, enabling direct tool transfer from R&D to production machines
- SUS304 stainless steel contact parts with easy-disassembly design for rapid batch changeover and cross-contamination prevention
- Small batch capability - as few as 50g of material required for preliminary compressibility assessment
- PLC data capture of compression force vs. displacement curves for Heckel plot analysis and material characterization
Q: Why is pre-compression important for formulation development?
Pre-compression de-aerates the powder bed before final compaction, eliminating capping and lamination defects that often mask true material behavior. The resulting tablet density and hardness data more accurately reflect what will be achieved on production-scale rotary presses.
Q: How much material is needed for a development run?
For preliminary compressibility screening, as little as 50g of formulation can produce enough tablets for basic characterization. A full development batch typically requires 200-500g depending on the number of compression parameter combinations being evaluated.
Q: Can shaped tablets be produced for development purposes?
Yes. Optional shaped tooling sets (oval, capsule, triangle, convex, concave) are available. Shaped tablets up to 23mm maximum length can be compressed, making this press suitable for developing specialty dosage forms.
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