Cholic Acid Stable Solubility Bile Acid Compound Biochemical Protein Stabilization

Cholic Acid (CAS 81-25-4) is a primary trihydroxy bile acid compound widely used in biochemical research, bile acid signaling study, membrane protein extraction, and pharmaceutical intermediate development. It delivers mild solubilization to maintain native protein conformation and enzymatic activity, supporting consistent experimental results and scalable synthesis.

• Chemical Name: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid
• CAS Number: 81-25-4
• Molecular Formula: C24H40O5
• Molecular Weight: 408.58 g/mol
• Appearance: White to off-white crystalline powder
• Solubility: Slightly soluble in water; soluble in ethanol, methanol, glacial acetic acid
• Stability: Stable under normal storage conditions; avoid strong light and high temperature
• Key Function: Mild non-denaturing detergent; FXR nuclear receptor ligand; bile acid pathway regulator

1. Biochemical Research: Used as mild detergent for membrane protein extraction and functional reconstitution.
2. Pharmaceutical Intermediate: Key raw material for bile acid derivative synthesis and impurity reference preparation.
3. Life Science Study: Applied in bile acid metabolism, FXR signaling pathway, and lipid regulation research.
4. Reference Standard: Used as analytical reference for quality control in bile acid related drugs and reagents.

• Produced under strict process control with full traceability.
• Tested by HPLC, melting point, loss on drying, heavy metals and other indicators.
• COA, MSDS, TDS documents available for download.

• Packaging: 1g, 5g, 25g, 100g, 500g, 1kg sealed bottles; custom bulk packaging supported.
• Storage: Keep in cool, dry, sealed environment; avoid direct sunlight and high temperature.
• Transportation: Non-hazardous for normal transportation; comply with international chemical logistics standards.