Anti Aging Recombinant Collagen I+III Dermal Filler Products NMPA Approval

1. Product Characteristics

• Bionic Compound Formula: Scientific compound ratio of Type I and Type III collagen highly simulates the structural proportion of natural young human skin, achieving comprehensive skincare effects that single collagen cannot realize.
• Animal-Free & Ultra-High Safety: Produced by microbial recombinant fermentation technology, free of animal-derived impurities, viruses and allergens, with ultra-low immunogenicity, no skin rejection, meeting medical and high-end cosmetic safety standards.
• Complete Active Molecular Structure: Adopts low-temperature gentle purification process to retain complete and stable triple-helix structure, featuring higher biological activity and skin absorption efficiency than ordinary fragmented collagen.
• High Stability & Biodegradability: Possesses stable physical and chemical properties, not easy to inactivate during processing and storage. It can be naturally degraded in human tissues without residue, belonging to eco-friendly safe biomaterials.

2. Technical Principle

• Human Gene Recombination Technology: Based on human native collagen gene sequences, target genes of Type I and Type III collagen are cloned and implanted into safe microbial strains. High-activity human-like recombinant collagen is obtained through precise fermentation, purification and molecular folding modification.
• Dual Collagen Synergy Mechanism: Type I collagen focuses on dermal structure support and anti-aging firming, while Type III collagen dominates epidermal repair and cell regeneration. The scientific compound ratio realizes multi-layer skin repair from epidermis to dermis.
• Active Molecular Self-Assembly: The complete triple-helix active structure can self-bind with human skin proteins after application, achieving rapid penetration and absorption, and activating the proliferation of endogenous collagen to maintain long-term skin vitality.

3. Technical Parameter List

• Collagen Type: Compound Recombinant Human Collagen (Type I + Type III)
• Protein Purity: ≥99%
• Molecular Structure: Complete triple-helix active structure
• Immunogenicity: Ultra-low, non-allergenic
• Biocompatibility: Medical grade, non-toxic and non-irritating
• Biodegradation Rate: 80%-90% within 30 days
• Storage Stability: Stable activity at -2℃ ~ 40℃

4. Application Scenarios

• High-End Functional Skincare: Suitable for anti-aging serums, firming essences, barrier repair creams and sensitive skin care products for daily skin moisturizing, soothing and anti-aging maintenance.
• Medical Aesthetic Post-Repair: Used as core raw material for medical repair dressings and postoperative repair gels, applicable for skin recovery after microneedle, phototherapy and minimally invasive cosmetic procedures.
• Biomedical Materials: Widely applied in biological wound dressings, tissue engineering scaffolds and skin regeneration auxiliary materials for clinical mild wound repair and skin tissue rehabilitation.
• High-Grade Personal Care: Applicable in body care and professional hair care products to improve dry skin and frizzy hair, realizing overall skin and hair nourishment and repair.