THROBIO PCL Polycaprolactone Powder Biological Thrombolytic Agent

• Product Description: Medical-grade PCL (Polycaprolactone) is a high-stability long-cycle biodegradable regenerative dermal filler, composed of uniform smooth PCL microspheres suspended in biocompatible CMC gel carrier. As one of the safest and most durable polyester biomaterials for aesthetic use, PCL features ultra-mild in-vivo degradation and zero acidic accumulation. It delivers dual aesthetic effects of instant volumizing filling and long-term endogenous collagen regeneration. Effectively improving facial hollowing, moderate to severe wrinkles, skin sagging and soft tissue atrophy, it builds delicate and firm facial contours. With ultra-long metabolic cycle and excellent tissue compatibility, it provides sustained progressive anti-aging and stable shaping effects for full-face rejuvenation and contour optimization.
• Product Features: PCL possesses unique ultra-mild degradation characteristics with no local acidic substance accumulation during metabolism, resulting in extremely low inflammatory response and superior safety compared with other polylactic acid fillers. It adopts high-sphericity and uniformly sized microspheres with smooth surface, ensuring excellent subcutaneous dispersion and integration without lump formation or granuloma risk. The dual-system formula combines immediate gel filling support and continuous microsphere regeneration, achieving stable volume maintenance without sudden shrinkage. It effectively stimulates synchronous regeneration of type I and type III collagen, significantly tightening loose skin and improving skin elasticity. Featuring ultra-long effective duration, low sensitization and natural shaping advantages, it adapts to long-term clinical anti-aging and delicate contour sculpting.
• Technical Principle: PCL is a synthetic aliphatic polyester polymer with stable long-chain molecular structure and excellent biological inertness. After subcutaneous injection, the CMC gel carrier provides immediate soft volume filling to quickly repair facial depressions and wrinkles. The evenly distributed PCL microspheres stably reside in deep dermal tissue, forming a three-dimensional bionic scaffold. Relying on slow, uniform and mild ester bond hydrolysis in physiological environment, PCL degrades steadily without rapid local metabolism or acid accumulation. During the long degradation cycle, it continuously activates fibroblast activity, induces ordered collagen hyperplasia and tissue remodeling. The regenerated autologous soft tissue gradually replaces the filler, finally achieving residue-free metabolism and forming long-lasting natural facial contour support.
• Production Process: Medical-grade PCL adopts high-precision microsphere polymerization and multi-stage sterile purification technology, fully produced in Class 100 dust-free constant-temperature sterile medical workshop. High-purity caprolactone monomers are selected and subjected to multi-stage refining, dehumidification and impurity removal to eliminate invalid components and residual toxins. Precise controllable polymerization and microsphere molding are carried out to form regular spherical PCL particles with uniform particle size and high sphericity. Multiple devolatilization, catalyst removal and ultrafiltration purification processes are applied to reduce endotoxin and residual monomers to ultra-low levels. After sterile homogenization, scientific proportioning with CMC gel carrier and vacuum sealing packaging, the finished products achieve stable batch consistency, smooth injection performance and ultra-high clinical safety.

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