Albumin powder GHL  High speed Wet Mixing  Granulator Machine (High shear granulation) (Granulating machine)( Granulating equipment, granulation equipment, Bottom-Drive Granulator);

Preface

YIBU” considers that the machine adopts horizontal cylinder structure, its structure reasonable. Air filled seal shaft for to drive. When washed , it can be changed to water. Fluidized Granulation, the granule is around ball shape. Its flow ability is good. Compared to traditional process, 25% of adhesive can be reduced and the drying time is short. The dry mixing time is 2 minutes and the granulating time is 1-4 minutes. Compared to the traditional process , 4-5 times of efficiency is raised.

Dry mixing ,humid mixing and granulating are finished in the same sealed container. It is in conformity with the requirements of GMP. The whole operation has strict safe and protective measures. Jacket type might be adopted on request

We have manufactured decades specifications and 150 different machines to meet different needs. These practical experiences will be very beneficial to customers.

High process efficiency through extremely fast drying and gentle product handling. Suitable for batches of 10 to 800Liter per batch .Further batch sizes available upon request；

Principle :

High shear granulation in a closed container with blending tools driven from above or below has long been applied by the pharmaceutical industry. The mechanical effect of the blending tools – irrespective of whether in batches or continuous operation – creates a denser granulate than the fluidized bed process.

Originally, the granulation liquid was poured into the product. Today, an improved dosed distribution using a spray nozzle is preferred in order to obtain a more even granulate.

The granules are distinguished by a compact structure and high bulk density. They have good flow characteristics and can be optimally pressed. For various applications in pharmaceuticals and related industries.

The electronic systems and their safety should comply with the requirements set forth in 21 CFR Part 11 and GMP Annex 11;

The data should be collected at appropriate time intervals and stored in the system in a fixed format that can be printed out/read;