Toxicology
Beijing Jitian-Biotech Co., Ltd. offers efficient dermal toxicology program. Accelerate the development of your new dermatology drug and biologic with our dermatological study services.
Our team has unique and extensive expertise in selecting optimal models for toxicology, efficacy, pharmacokinetics and pharmacology studies. Our experts will move your program toward regulatory submission in an efficient and timely manner.
Our facility was capable of housing small and large animals. We have a fully equipped, state of the art histopathology lab in house to support your preclinical program.

Dermal Toxicology Studies
● Acute dermal toxicity studies
● Acute single or multiple dose dermal toxicity studies
● Two week-long term dermal toxicity studies (with or without recovery period)
● Acute perivascular irritation studies
● DTH and hypersensitization studies
● Phototoxicity and ultraviolet light studies
● Skin irritation studies to intact or abraded skin

Ocular Toxicology Studies
● Contact lens toxicology
● Contact lens toxicity
● Lacrimation assessment
● Multiple-dose subacute and chronic ocular toxicity
● Ocular gene therapy and regenerative medicine studies
● Tolerability testing
● Ocular irritation, tolerability and sensitization studies
● Ocular sensitization
● Ocular toxicology
● Punctal plug toxicity
● Punctal plug toxicology
● Pupillary diameter testing
● Single-dose ocular toxicity
● Ocular implant toxicology

ROUTES OF ADMINISTRATION
● Standard routes
● Intravesicular
● Intravaginal
● Intrarectal
● Intranasal
● Intradermal
● Ocular
● Aural-otic
● Buccal
● Patches
● Devices
● Device-drug combination
● Infusion
● Dermal
● Topical
● Wounds
● Sublingual
● Nanoparticles
● Device stem cell combination
● Intrathecal
● Intracerebral
● Intratumoral
● Intracardiac
● Intra-intestinal
● Others upon request

TYPES OF TOXICOLOGY STUDIES

Acute Studies
 ● Acute
 ● Dose ranging
 ● Limit dosing
 ● Maximum tolerated dose
 ● Single dose

Subacute & Subchronic
 ● 1-week subacute
 ● 2-week subacute
 ● 4-week subchronic
 ● 8-week subchronic

Chronic & Carcinogenicity
 ● 3-month chronic
 ● 6-month chronic
 ● 9-month chronic
 ● 1-year carcinogenicity
 ● 2-year carcinogenicity

Special or custom toxicology
 ● 1-year chronic
 ● 2-year chronic
 ● Stem cells
 ● Surgical toxicity
 ● Transgenic carcinogenicity
 ● Others upon request