Food‑grade Ginsenoside CK for stamina‑boost blood‑nourishing formulations
Price:
FOB Shanghai USD145/100g
MOQ:
100g
Delivery Time:
10-20 work days
Brand:
NUGLY
Product Description
Product Overview
Ginsenoside Compound K (CK) — CAS: 39262-14-1 — is a rare deglycosylated protopanaxadiol-type ginsenoside produced via enzymatic bioconversion from major ginsenosides Rb1, Rb2 and Rc.
With superior oral bioavailability and tissue distribution, CK has been studied for its hematopoietic support, microcirculation improvement and vitality-enhancing properties. It supports red blood cell antioxidant defense, promotes peripheral blood flow, and enhances cellular energy metabolism — making it a premium functional ingredient for blood wellness, fatigue relief and physical vitality formulas.
Compliance Note: CK is a natural dietary raw material, All claims are based on preclinical study data.
Physicochemical Properties
|
Parameter
|
Specification
|
|---|---|
|
Chemical Name
|
20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol
|
|
Molecular Formula
|
C₃₆H₆₂O₈
|
|
Molecular Weight
|
622.88 g/mol
|
|
CAS No.
|
39262-14-1
|
|
Appearance
|
White to off-white crystalline powder
|
|
Melting Point
|
181–183 °C
|
|
LogP (Lipophilicity)
|
5.50
|
|
Solubility
|
Soluble in methanol, ethanol, DMSO; slightly soluble in water
|
|
Purity (HPLC)
|
98% / 95% / 80% available
|
|
Production
|
Enzymatic hydrolysis / microbial biotransformation
|
Blood Nourishment & Vitality Mechanism
Optimal blood health relies on balanced hematopoiesis, efficient microcirculation, adequate oxygen transport and sustained cellular energy. Ginsenoside CK supports blood wellness through multiple complementary pathways:
1. Support Hematopoietic Function
CK promotes proliferation of hematopoietic progenitor cells and upregulates hematopoietic growth factor expression. It supports bone marrow hematopoietic activity and helps maintain healthy red blood cell production under physiological stress conditions.
2. Improve Microcirculation & Peripheral Blood Flow
CK enhances nitric oxide (NO) production in vascular endothelium, promoting vasodilation and improving peripheral microcirculation. This helps enhance tissue perfusion and nutrient delivery to distal organs and extremities.
3. Protect Red Blood Cell Antioxidant Defense
CK activates Nrf2/ARE antioxidant pathway, reducing oxidative damage to erythrocyte membranes. It helps maintain red blood cell membrane integrity, deformability and oxygen-carrying capacity under oxidative stress.
4. Enhance Cellular Energy Metabolism
CK improves mitochondrial function and ATP production in peripheral tissues. It optimizes oxygen utilization efficiency, reduces lactic acid accumulation during physical exertion, and supports sustained physical stamina.
5. Relieve Physical Fatigue & Boost Vitality
By improving blood flow, oxygen delivery and energy metabolism, CK helps alleviate physical fatigue associated with poor circulation and sub-health status, supporting overall physical vitality and well-being.
Core Mechanism Summary: Ginsenoside CK supports blood wellness through a synergistic approach — enhancing hematopoietic activity, improving microcirculation, protecting erythrocyte integrity, boosting energy metabolism and relieving physical fatigue.
Research Data
All data derived from peer-reviewed preclinical studies (cell & animal models). Not clinical human trial data.
In Vitro Data
|
Marker
|
Control Group
|
CK Treatment
|
|---|---|---|
|
Hematopoietic progenitor cell proliferation
|
100% (baseline)
|
↑ 35–52%
|
|
Erythrocyte hemolysis (oxidative stress)
|
100% (damage)
|
↓ 40–55%
|
|
Endothelial NO production
|
100% (baseline)
|
↑ 45–65%
|
|
ATP production (muscle cells)
|
100% (baseline)
|
↑ 28–40%
|
|
Nrf2 nuclear translocation
|
1.0× baseline
|
↑ 2.3×
|
In Vivo Data
- Anti-fatigue swimming test: CK 50 mg/kg significantly extended exhaustive swimming time by ~68%, with reduced blood lactic acid and increased liver glycogen storage.
- Microcirculation model (mesentery): CK improved microvascular flow velocity by ~42% and increased capillary density in peripheral tissues.
- Hematopoietic support model: CK treatment increased red blood cell count and hemoglobin levels in anemia-induced animal models, supporting hematopoietic recovery.
- Cold extremities model: CK improved peripheral blood flow in distal extremities, raising skin temperature and reducing cold-induced vasoconstriction.
- Exercise recovery: CK reduced post-exercise creatine kinase (CK) and lactic dehydrogenase (LDH) levels, supporting faster recovery from physical exertion.
Application Fields
- Blood circulation & vitality supplements
- Anti-fatigue & stamina boost formulas
- Hematopoietic wellness dietary ingredients
- Cold extremities & poor circulation support
- Sub-health fatigue recovery products
- Sports nutrition & endurance formulas
- Post-illness vitality restoration support
- Iron-deficiency support (adjunctive ingredient)
Product Advantages
- Multi-pathway blood support — hematopoiesis, microcirculation, RBC protection and energy metabolism combined
- High bioavailability — deglycosylated structure ensures superior absorption and systemic distribution
- Endothelial NO enhancement — improves vascular function and peripheral blood flow naturally
- Strong anti-fatigue evidence — validated in multiple exercise endurance and recovery models
- Controllable enzymatic production — stable purity, low impurity, batch-to-batch consistency
- Good safety profile — low acute toxicity, suitable for long-term daily supplementation
Recommended dosage:
Rg3 5-20mg/d
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Company
Zhongke Runxin (Suzhou) Biotechnology Co., Ltd
Location
No.6 Anmin Road,Huangdai Town,Xiangcheng District,Suzhou City
Contact Person
Zhang