Premium Chicken Bone Peptone with Controlled Enzymatic Digestion for Balanced Amino Acid Profile and Batch-to-Batch Reproducibility
Premium Chicken Bone Peptone — Advanced Nitrogen Base for Precision Microbial Cultivation
Product Introduction
Premium Chicken Bone Peptone represents a specialized nitrogen substrate engineered from high-quality poultry bone stock using controlled enzymatic digestion technology. This product delivers consistent nutrient availability for industrial fermentation processes, clinical microbiology applications, and biopharmaceutical production systems. The balanced amino acid profile supports optimal microbial physiology while maintaining batch-to-batch reproducibility.
Source Material Specifications
| Parameter | Requirement |
|---|---|
| Raw Material | Fresh chicken bone from regulated processing facilities |
| Quality Standard | Free from decomposition, pathological tissue, and foreign matter |
| Handling Protocol | Refrigerated transport and processing within 12 hours |
| Documentation | Complete chain-of-custody records maintained |
Production Technology
| Process Step | Operating Conditions |
|---|---|
| Bone Preparation | Mechanical reduction, thermal treatment, fat separation |
| Hydrolysis Phase | Enzyme-assisted digestion with pancreatic proteases |
| Purification Sequence | Depth filtration, carbon treatment, sterile filtration |
| Concentration | Low-temperature vacuum evaporation |
| Drying Method | Controlled spray drying with particle classification |
| Quality Assessment | In-process monitoring and final release testing |
Performance Advantages
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Nitrogen Accessibility – Dual nitrogen fractions support both rapid growth and sustained metabolism
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Solution Characteristics – Complete solubility with thermal stability; no precipitation under standard sterilization
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Low Interference – Reduced mineral content minimizes osmotic effects and media precipitation
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Process Consistency – Statistical process control ensures reproducible fermentation outcomes
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Versatile Application – Compatible with aerobic and anaerobic cultivation systems
Quality Parameters
| Test Parameter | Method Reference | Unit | Specification | Lot Verification |
|---|---|---|---|---|
| Total Nitrogen | Kjeldahl method | % | 14.0 – 15.5 | 14.8 |
| Amino Nitrogen | Formol titration | % | ≥ 2.5 | 2.9 |
| Sodium Chloride | Volhard titration | % | ≤ 5.0 | 2.3 |
| Moisture Content | Gravimetric (105°C) | % | ≤ 6.0 | 4.2 |
| Ash Content | Gravimetric (550°C) | % | ≤ 6.0 | 4.5 |
| pH Value | Potentiometric (2% solution) | — | 5.0 – 7.0 | 5.6 |
| Physical Form | Visual inspection | — | Light yellow powder | Conforms |
| Solution Appearance | 2% solution, boiled then cooled | — | Clear, no sediment | Conforms |
| Alkaline Stability | pH 8-9, 121°C, 20 min | — | No precipitate | Conforms |
| Nitrite Detection | Griess reaction | — | Not detectable | Conforms |
Biological Performance Profile
| Test Category | Test Organisms | Expected Pattern | Observed Result |
|---|---|---|---|
| Sulfur Metabolism | S. Typhi / Shigella | + / – | Confirmed |
| Tryptophan Utilization | E. coli / S. Typhi | + / – | Confirmed |
| Glucose Metabolism | E. aerogenes / E. coli | + / – | Confirmed |
| Sugar Fermentation | E. coli / S. Typhi | No acid formation | Confirmed |
| Erythrocyte Interaction | S. pneumoniae / β-streptococcus | α / β patterns | Stable through passages |
| Pigment Expression | P. aeruginosa / S. aureus | Green / Golden | Stable through passages |
| Colony Formation | E. coli / S. aureus | ≥1.0mm, smooth morphology | Confirmed |
| Dilution Support | β-streptococcus / Gram-positive bacillus | 10⁻⁴ / 10⁻⁵ growth | Confirmed |
Industry Applications
| Sector | Application Type | Typical Usage Level |
|---|---|---|
| Biopharmaceutical Manufacturing | Bacterial fermentation, toxoid production | 1.0 – 2.0% |
| Industrial Enzyme Production | Protease, amylase, lipase fermentation | 1.5 – 2.5% |
| Diagnostic Media Production | Dehydrated culture media, selective formulations | 1.0 – 1.5% |
| Research Laboratories | Microbial physiology, strain development | Variable |
| Probiotic Manufacturing | Biomass accumulation, viability optimization | 1.5 – 2.0% |
Packaging Details
| Component | Description |
|---|---|
| Inner Packaging | Food-grade polyethylene liner, heat-sealed closure |
| Outer Packaging | Multi-wall kraft paper bag or polywoven sack |
| Net Weight | 20.0 kg per unit |
| Pallet Load | 40 bags (800 kg) per pallet |
| Identification | Product name, lot number, manufacture date, net weight |
Storage Guidelines
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Temperature Range: 10 – 30°C
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Humidity Control: Store in dry conditions, avoid moisture absorption
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Light Protection: Keep away from direct sunlight
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Shelf Life: 24 months from production date
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After Opening: Use within 30 days; reseal container tightly after each use
Quality Systems Compliance
| Element | Standard Reference |
|---|---|
| Manufacturing Facility | GMP-compliant production environment |
| Product Specification | Enterprise standard Q/SCSH 003-2025 |
| Reference Standard | Chinese Biological Products Raw Material Control Standard (2000) |
| Testing Methods | National food safety standards (GB series) |
| Batch Documentation | Complete traceability with Certificate of Analysis |
For technical specifications, sample evaluation, or customized product development, please contact our technical sales team.
Get in Touch
Have questions about our products or want to discuss a custom order? Our team is ready to help you.