Immunocytochemistry P16 Protein Staining Test Kit Biomarker Tumor Suppressor
ICC Test Kits Immunocytochemistry P16 Protein Staining Test Kit Biomarker Tumor Suppressor
Product Name
Keypath p16 Immunoassay Test Kit (ICC)
Introduction
p16 is a protein that slows cell division by slowing the progression of the cell cycle from the G1 phase to the S phase, thereby acting as a tumor suppressor. It is encoded by the CDKN2A gene. A deletion (the omission of a part of the DNA sequence during replication) in this gene can result in insufficient or non-functional p16, accelerating the cell cycle and resulting in many types of cancer.
p16 is a biomarker to improve the histological diagnostic accuracy of grade 3 cervical intraepithelial neoplasia (CIN). p16 is also implicated in the prevention of melanoma, oropharyngeal squamous cell carcinoma, cervical cancer, vulvar cancer and esophageal cancer.
Product Information
| Name | Keypath p16 Immunoassay Test Kit(ICC) |
| Applied to | Detection of cervical cancer by cervical epithelial cells |
| Composition | p16 antibody reagent, PBST (20×), Antigen repair solution (50×), Blocker, Penetrant, HRP labeked secondary antibody, Chromogenic solution A, Chromogenic solution B, Hematoxylin restaining solution, Bluing solution, Instruction for Use |
|
Signal at |
Nucleus/plasma |
| Positive judgement | Nucleus/plasma colored in tan or tan coloration |
| Specification | 25Tests/Kit; 50Tests/Kit; 100Tests/Kit |
| Size of packing box | 140*97*73 mm |
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