Factory Supply Wholesale Price Salvia Miltiorrhiza Extract CAS 35825-57-1 5%-98% Cryptotanshinone
Cryptotanshinone Powder
What is Cryptotanshinone Powder?
Cryptotanshinone is a tanshinone-type diterpenoid compound isolated from Salvia miltiorrhiza and is a lipid-soluble component. Its chemical structure is characterized by a tanshinone-type core and specific substituents. This structure is closely related to its pharmacological activity. As a tanshinone-type diterpenoid compound extracted from Salvia miltiorrhiza, it possesses multiple pharmacological activities, including antiviral, anti-inflammatory, and antiplatelet aggregation effects.
Feature
Anti-inflammatory and Immunomodulatory Effects: Cryptotanshinone inhibits the expression of nitric oxide synthase and cyclooxygenase-2 in macrophages, reducing the production of inflammatory mediators. It can regulate the balance of T lymphocyte subsets, inhibit excessive immune responses, and show ameliorative effects on experimental arthritis and colitis.
Antibacterial and Anti-acne Activity: This component has a significant inhibitory effect on common skin pathogens such as Propionibacterium acnes and Staphylococcus aureus. Its orthoquinone structure may interfere with electron transport in the microbial respiratory chain. It can inhibit excessive proliferation of sebaceous gland cells and lipid synthesis, alleviating acne development from multiple aspects.
Cardiovascular Protection: Cryptotanshinone can dilate coronary arteries, improve myocardial microcirculation, and reduce ischemia-reperfusion injury through antioxidant mechanisms. It has antiplatelet aggregation and antithrombotic effects, helping to maintain smooth blood flow.
Anti-tumor and Differentiation Induction: Studies have shown that cryptotanshinone can induce cell cycle arrest and apoptosis in tumor cells, possibly through regulation of signaling pathways such as PI3K/Akt. It has differentiation-inducing activity on some leukemia cells, promoting the transformation of malignant cells into normal phenotypes.
Applications
Acne Treatment and Skin Care: Used as an active ingredient in prescription drugs or cosmetics for the treatment of mild to moderate inflammatory acne in topical gels and creams. Added to oil-controlling and anti-acne skincare products to improve oily skin and enlarged pores.
Cardiovascular Disease Adjunctive Treatment: Used in traditional Chinese medicine compound preparations (such as tanshinone tablets) for coronary heart disease and angina pectoris to help improve symptoms of myocardial ischemia. Also used as an adjunctive treatment ingredient for microcirculation disorders (such as diabetic peripheral neuropathy).
Inflammatory Diseases and Immune Regulation: Used as an adjunctive treatment for chronic inflammatory diseases such as rheumatoid arthritis and pelvic inflammatory disease. Developed as a health food to regulate immune balance, suitable for people with inflammatory constitutions.
Product Parameters
| Test items | Specifications |
| Assay | ≥ 10.0% Cryptotanshinone |
| Appearance | Brown Red Fine Powder |
| Odor and Taste | Characteristic |
| Sieve analysis | Through 80 mesh |
| Loss on Drying | ≤5.0 % |
| Total Ash | ≤5.0 % |
| Bulk Density | 40~60 g/100mL |
| Tap Density | 50~80g/100mL |
| Lead (Pb) | <3.0mg/kg |
| Arsenic (As) | <2.0mg/kg |
| Cadmium (Cd) | <1.0mg/kg |
| Mercury (Hg) | <0.1mg/kg |
| Total Aerobic Count | ≤ 1000cfu/g |
| Yeast & Moulds | ≤ 100cfu/g |
| E-Coli | Negative |
| Salmonella | Negative |
| Staphylococcus Aureus | Negative |
For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin
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