IVDR Certified DNA Selection Beads for NGS Library Preparation

IVDR Certified DNA Selection Beads for NGS Library Preparation

Company profile

BunnyTeeth Technology Inc. is committed to building a complete core technology platform for bioengineering, building a high-quality biotech product chain and a technical service chain, with the ambition to become a global leader in molecular and genetic diagnostic. BunnyTeeth Technology Inc. will also provide customers with a full-range of one-step service solution in the field of molecular diagnostics and genetic diagnostic.

Product briefing

Product illustration

SPRI (Solid Phase Reverse Immobilization), uses paramagnetic beads to selectively bind nucleic acids by type and size, which can be used to isolate, purify and clean up high purity nucleic acids. The technology can be applied to next-generation sequencing (NGS), Sanger sequencing, qPCR, ddPCR and microarrays, etc. IVDR Certified DNA Selection Beads for NGS Library Preparation uses high performance magnetic beads and a unique buffer system that allows for the adjustment of the ratio of magnetic beads to sample to achieve selection and purification of DNA fragments from 100bp-10kb.

Key characteristics

1. Super Paramagnetic
2. Fast magnetic response
3. High surface area
4. Uniform size
5. Rich carboxyl functional group
6. Low CV

Product performance

1. Technique:Super paramagnetic beads, which are rapidly aggregated in the magnetic field; uniform size to ensure sufficient magnetic responsiveness without settling; buffer optimized by multiple rounds of proportioning
2. Production:Full set of reagents are manufactured in GMP production factory with ISO13485 standard; control the source production process, use scientific verification system with industry gold standard
3. Application:Thousands of clinical samples tested in the NGS testing laboratory of Geneseeq (CAP & CLIA certified), with stable results and expected performance indicators

Figure 1. The recovery efficiency of magnetic beads is highly consistent with competitive products.

Using different ratios of IVDR Certified DNA Selection Beads for NGS Library Preparation and Ampure XP beads to purify and recover the same amount of DNA fragments, the recovery of IVDR Certified DNA Selection Beads for NGS Library Preparation is highly consistent with Ampure XP beads.

Composition

Structure of magnetic beads(3-layer):

Innermost core is Polystyrene (PS)

Second layer wrapped with magnetic material——Fe3O4

The outermost surface is a polymer modified by carboxyl groups(-COOH)

Storage condition

Store at 2-8°C upon arrival (not freeze), for up to 12 months.

Operating procedure