150L Low Temperature/ Refrigerated BOD Incubator NovaIncu BOD-150A

Features:

• Combines a stainless steel work chamber with a durable powder-coated exterior.
• Double-door design and large glass window provide safety and clear visibility.
• Intelligent compressor system auto-manages defrosting and operating pressures.
• Engineered for low temperature variance and quiet, energy-efficient operation.
• 3D uniform heating technology eliminates cold spots for consistent results.
• Integrated illumination and a standard power outlet add user convenience.
• High-performance digital controller allows for precise setpoint adjustment.
• Supports long-duration tests with preset programming up to 99 hours.
• Alerts for sensor failure, deviations, and over-temperature conditions.
• Optional accessories include a dual-protection safety module and a UV lamp.

Specifications

Introduction about incubator

Structural biology efforts to solve the architecture of membrane proteins (like GPCRs or ion channels) often begin with their expression in heterologous systems, a process reliant on incubators.

These proteins are typically expressed in insect or mammalian cells (e.g., using the baculovirus system in insect cells). Culturing these cells at the correct temperature (e.g., 27-28°C for insect cells) and with proper aeration in a shaking incubator is the first critical step to obtain sufficient biomass. After expression, the cells are harvested, and the fragile membrane proteins are extracted with detergents. Subsequent purification steps might require incubation at 4°C in a refrigerated cabinet or cold room to maintain stability.

Finally, the crucial step of crystallization often involves incubating droplets of purified protein with precipitant solutions at a constant, vibration-minimized temperature (e.g., 4°C, 20°C) for days to weeks. Specialized, low-vibration incubators or warm rooms are used for these crystallization trays. A stable thermal environment throughout this multi-week pipeline is essential to produce the high-quality, ordered crystals needed for X-ray diffraction, enabling medicine design targeting these important therapeutic targets.