Shanxi Zorui Biotechnology Co., Ltd.
                                                                                                           
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medical-Grade Bismuth Subgallate Powder CAS 99-26-3 - Astringent Hemostatic Ingredient for Hemorrhoid Treatment

Price Negotiable
Price: Negotiable
MOQ: 500g, 1kg or 25kg for sample, 1000kg for commercial order
Delivery Time: In 3 working days
Brand: Zorui
Product Description
Bismuth Subgallate Powder (CAS 99-26-3) Hemorrhoid Treatment Ingredient
Bismuth Subgallate (CAS 99-26-3) is a medical-grade complex of bismuth and gallic acid, renowned for its astringent, antiseptic, and hemostatic properties. This odorless, bright yellow powder is insoluble in water, making it ideal for gastrointestinal medications, wound care, and dermatological formulations. Compliant with USP/EP standards, it offers safe, effective management of skin irritation, minor bleeding, and digestive disorders.
Physical and Chemical Specifications
Property Specification
CAS Number 99-26-3
Molecular Formula C7H5BiO6
Appearance Bright yellow amorphous powder
Bismuth Content 46-52% (w/w)
Solubility Insoluble in water, ethanol; soluble in dilute acids/alkalies
Loss on Drying ≤ 1.0%
Heavy Metals (Pb) ≤ 20 ppm
Storage 15-25°C (protected from light)
Product Functions
  • Astringent: Contracts tissues to reduce secretions/bleeding
  • Antiseptic: Mild antibacterial action against skin pathogens
  • Hemostatic: Promotes clot formation in minor wounds
  • Gastroprotective: Forms protective coating in GI tract
  • Radiopacity: Enhances visibility in X-ray diagnostics
Application Areas
  • medicals: Ointments/powders for hemorrhoids, ulcers, and skin irritation; GI medications (anti-diarrheal, gastritis relief)
  • Medical Devices: Radiopaque marker in surgical dressings
  • Cosmetics: Soothing agent in diaper rash creams
  • Veterinary: Topical wound management for animals
Manufacturing Process
  1. Reaction: Gallic acid reacts with bismuth nitrate in aqueous solution
  2. Precipitation: Alkaline pH adjustment to form insoluble Bismuth Subgallate
  3. Purification: Washing to remove nitrates and residual solvents
  4. Drying: Vacuum drying at ≤60°C to preserve stability
  5. Milling: Sieving to uniform particle size (90% < 100µm)
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  • Pharma-Grade Purity: >99% assay; USP/EP/JP compliance
  • Low Toxicity: Meets ICH Q3D guidelines for elemental impurities
  • Customization: Particle size (10-200µm), sterile options (gamma-irradiated)
  • Certifications: GMP, ISO 9001, REACH, Halal/Kosher upon request
  • Supply Chain: Batch traceability, 24-month shelf life, cold-chain shipping
Frequently Asked Questions

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Is Bismuth Subgallate safe for open wounds?
Yes, it's USP-monographed for topical hemostasis and wound protection.
Why does stool turn black after ingestion?
Normal reaction - bismuth forms black sulfide in GI tract (harmless).
Can it replace bismuth subsalicylate (Pepto-Bismol ®)?
Similar GI benefits but without salicylates (safer for aspirin-sensitive patients).
Shelf life and storage?
24 months unopened; store below 25°C away from light/moisture.
Is it vegan-friendly?
Gallic acid is plant-derived (tannins), but confirm sourcing for strict vegan needs.
Product Images
Bismuth Subgallate chemical structure and sample Bismuth Subgallate industrial packaging and storage Bismuth Subgallate laboratory testing and quality control Bismuth Subgallate applications in various industries

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Company Shanxi Zorui Biotechnology Co., Ltd.
Location No.1107 Triumph Building 6, Yongtai St., Pingcheng District, Datong, Shanxi, China
Contact Person Julie

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