High-Purity Salicylic Acid 2-Hydroxybenzoic acid Keratolytic Action Anti-inflammatory Properties for Medical
Salicylic Acid (CAS 69-72-7) is a vital beta-hydroxy acid (BHA) and organic compound renowned for its exceptional keratolytic, anti-inflammatory, and antiseptic properties. Derived from willow bark and now synthesized for high purity, it is a cornerstone ingredient in dermatology, acne treatments, medicals, and industrial applications. Our Salicylic Acid meets the highest pharmacopeial standards (USP/BP/EP), ensuring superior efficacy and safety for your formulations.
| Property | Specification |
|---|---|
| CAS Number | 69-72-7 |
| Molecular Formula | C₇H₆O₃ |
| IUPAC Name | 2-Hydroxybenzoic acid |
| Appearance | White crystalline powder or needle-shaped crystals |
| Odor | Odorless |
| Purity | ≥ 99.5% |
| Melting Point | 158-161°C |
| Boiling Point | 211°C (at 20 mmHg) |
| Density | 1.44 g/cm³ |
| Solubility | Soluble in ethanol; slightly soluble in water |
| pH (Saturated Solution) | ~2.4 |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.05% |
| Heavy Metals (as Pb) | ≤ 10 ppm |
| Sulfate Ash | ≤ 0.1% |
| Storage | Store in a cool, dry, well-ventilated area away from incompatible substances. |
- Keratolytic Action: Penetrates pores to dissolve excess sebum and dead skin cells, effectively unclogging pores and preventing comedones.
- Anti-inflammatory: Reduces redness, swelling, and irritation associated with acne and other skin conditions.
- Antibacterial: Exhibits mild antibacterial and antifungal properties, helping to control microbial growth on the skin.
- Cornific Agent: Promotes the shedding of the outer skin layer, making it essential for treating psoriasis, warts, calluses, and dandruff.
- Chemical Peel Agent: Used in controlled concentrations for professional skin peels to improve skin texture and tone.
- Cosmetics & Skincare: Acne cleansers, spot treatments, toners, serums, exfoliating peels, anti-dandruff shampoos, and wart removers.
- Medicals: Used in topical ointments, creams, plasters (e.g., corn plasters), and medicated powders.
- Food Preservation: Used as a preservative (E-number E914) in certain applications due to its antifungal properties.
- Industrial & Chemical Synthesis: Key intermediate in the production of aspirin (acetylsalicylic acid), dyes, fragrances, and other fine chemicals.
- Agriculture: Utilized in some plant hormone formulations.
We employ a state-of-the-art Kolbe-Schmitt synthesis process, ensuring optimal purity and batch-to-batch consistency:
- Phenolation: Sodium phenoxide is reacted with carbon dioxide under controlled temperature and pressure.
- Carboxylation: Formation of the sodium salt of salicylic acid.
- Acidification: The sodium salt is treated with a strong mineral acid (e.g., sulfuric acid) to precipitate crude Salicylic Acid.
- Purification: Multiple stages of recrystallization and washing are performed to achieve medical-grade purity (>99.5%).
- Drying & Milling: The purified crystals are dried under vacuum and milled to specified particle sizes.
- Quality Control: Every batch undergoes rigorous HPLC, GC, and spectroscopic analysis to confirm identity, potency, and absence of impurities.
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Contact our team for a competitive quote, free sample, or technical consultation. Worldwide shipping available with custom packaging options.
Request a QuoteRequest Free Sample- High Purity Guaranteed: We supply 99.5%+ pure Salicylic Acid compliant with USP, BP, EP, and FCC standards.
- Global Supply Chain: Reliable logistics ensuring on-time delivery to customers worldwide.
- Technical Expertise: Over [X] years of experience in fine chemical manufacturing with dedicated R&D and application support.
- Customization: Available in various mesh sizes (powder/granular) and tailored packaging (from 1kg to 25kg drums).
- Certifications: Our facility is ISO 9001, ISO 14001, and cGMP certified, guaranteeing quality and safety.
- Competitive Pricing: Direct manufacturer pricing without intermediaries, offering excellent value.
A: For over-the-counter (OTC) leave-on products, concentrations typically range from 0.5% to 2%. For rinse-off products like cleansers, it can be higher. Professional peels may use up to 30%. Always formulate within safe and regulatory limits for your target market.
A: Yes. Our product meets stringent pharmacopeial monographs (USP/BP/EP) and is manufactured in a cGMP-compliant facility, making it ideal for API use in topical medicals.
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Contact our team for a competitive quote, free sample, or technical consultation. Worldwide shipping available with custom packaging options.
Request a QuoteRequest Free SampleA: Store in a tightly closed container in a cool, dry, well-ventilated area away from heat, moisture, and incompatible materials like strong oxidizers and bases.
A: Our standard MOQ is 25kg, but we offer flexibility for sample orders and new partnerships. Please contact our sales team for specific inquiries.
A: Absolutely. A comprehensive TDS and a batch-specific CoA are provided with every shipment to ensure full transparency and quality assurance.
A: Yes. We provide private labeling services and can discuss custom synthesis for derivatives or specific particle size requirements. Contact us to discuss your project needs.





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