Cell Free DNA BCT for Genetic Diagnostic (Next Generation Sequencing)

Cell Free DNA BCT for Genetic Diagnostic (Next Generation Sequencing)

Company info

BunnyTeeth Technology Inc. is committed to building a complete core technology platform for bioengineering, building a high-quality biotech product chain and a technical service chain, with the ambition to become a global leader in molecular and genetic diagnostic. BunnyTeeth Technology Inc. will also provide customers with a full-range of one-step service solution in the field of molecular diagnostics and genetic diagnostic.

Product info

Product description:

The role of plasma cell-free DNA (cfDNA) is becoming increasingly evident as an important test sample for tumor diagnosis and non-invasive prenatal screening. BunnyTube Cell Free DNA BCT for Genetic Diagnostic (Next Generation Sequencing) can be directly used for whole blood collection, preservation and transportation, which can effectively protect cfDNA from degradation by nucleases and avoid the release of genomic DNA from blood nucleated cells, greatly ensuring the downstream application of cfDNA.

Advantage

1. Technique:Use EDTA-K3 as anticoagulant, which has highest solubility in the liquid, to bind to Ca²⁺ ions in blood to form chelates, and inhibit thrombospondin activation to prevent blood clotting.
2. Production:Full set of reagents are manufactured in GMP production factory with ISO13485 standard; control the source production process, use scientific verification system with industry gold standard
3. Application:Thousands of clinical samples tested in the NGS testing laboratory of Geneseeq (CAP & CLIA certified), with stable results and expected performance indicators.

Figure 1. Hemolysis of blood samples and stable cfDNA yield at different storage times.

Blood samples were collected into 3 brands of preservation tubes, and the samples were placed at room temperature for 0, 3, 7 and 14 days to compare the hemolysis and cfDNA yield. BunnyTube cfDNA Preservation Tube for Body Fluid and Non-invasive Pre-natal Screening Genetic Testing CE Certified could effectively inhibit hemolysis and the extracted cfDNA yield was stable.

Component

Storage condition

Storage Temperature: 10- 30 ℃

Shelf life: 12 months

Applied Scene

1. Fetal non-invasive birth defect screening (non-invasive Down's syndrome test)
2. Tumor biomarker discovery and research
3. Oncology treatment and efficacy assessment studies
4. Clinical drug development and testing
5. Related disease molecular level research