DNA Clean-up & Fragment Selection Beads for Next Generation Sequencing with Extracted DNA & PCR Product

DNA Clean-up & Fragment Selection Beads

for Next Generation Sequencing with Extracted DNA & PCR Product

Company profile

BunnyTeeth Technology Inc. is committed to building a complete core technology platform for bioengineering, building a high-quality biotech product chain and a technical service chain, with the ambition to become a global leader in molecular and genetic diagnostic. BunnyTeeth Technology Inc. will also provide customers with a full-range of one-step service solution in the field of molecular diagnostics and genetic diagnostic.

Product briefing

Product illustration

DNA Clean-up & Fragment Selection Beads for Next Generation Sequencing with Extracted DNA & PCR Product are based on the SPRI (Solid Phase Reversible Immobilization) para-magnetic technology, which can selectively bind nucleic acid fragments of different sizes by adjusting the volume ratio between the beads and the sample to meet the needs of different length of nucleic acids, and are suitable for purification and screening of ideal size DNA fragments in high-throughput sequencing. The product is compatible with various brands of DNA and RNA library preparation kits, and can perfectly replace AMPure XP Beads and Axygen Beads, which are widely used in various NGS platforms.

Key characteristics

1. Super Paramagnetic
2. Fast magnetic response
3. High surface area
4. Uniform size
5. Rich carboxyl functional group
6. Low CV

Product performance

1. Technique:Super paramagnetic beads, which are rapidly aggregated in the magnetic field; uniform size to ensure sufficient magnetic responsiveness without settling; buffer optimized by multiple rounds of proportioning
2. Production:Full set of reagents are manufactured in GMP production factory with ISO13485 standard; control the source production process, use scientific verification system with industry gold standard
3. Application:Thousands of clinical samples tested in the NGS testing laboratory of Geneseeq (CAP & CLIA certified), with stable results and expected performance indicators

Figure 1. The recovery efficiency of magnetic beads is highly consistent with competitive products.

Using different ratios of DNA Clean-up & Fragment Selection Beads for Next Generation Sequencing with Extracted DNA & PCR Product and Ampure XP beads to purify and recover the same amount of DNA fragments, the recovery of DNA Clean-up & Fragment Selection Beads for Next Generation Sequencing with Extracted DNA & PCR Product is highly consistent with Ampure XP beads.

Composition

Structure of magnetic beads(3-layer):

Innermost core is Polystyrene (PS)

Second layer wrapped with magnetic material——Fe3O4

The outermost surface is a polymer modified by carboxyl groups(-COOH)

Storage condition

Store at 2-8°C upon arrival (not freeze), for up to 12 months.

Operating procedure