Product Description:

Salmonella Rapid Test is an in vitro qualitative Immunochromatographic assay for the rapid detection of S. Typhi antigens in human stool specimen. The test are intended to help in the diagnosis of S. Typhi infection and to monitor the effectiveness of therapeutic treatment.

Typhoid fever is a life threatening illness caused by the bacterium Salmonella typhi, and was observed by Eberth (1880) in the mesenteric nodes and spleen of fatal cases of typhoid fever. The infection is acquired typically by ingestion. On reaching the gut, the bacilli attach themselves to the epithelial cells of the intestinal villi and penetrate to the lamina and submucosa. They are then phagocytosed there by polymorphs and macrophages. The ability to resist intracellular killing and to multiply within these cells is a measure of their virulence. They enter the me senteric lymph nodes, where they multiply and, via the thoracic duct, enter the blood stream.

The test uses new homogenous immunochromatographic system with gold particules. It is a ready to use test which only needs a faecal sample dilution with the supplied ready to use dilution buffer. Specificity is ensured by using a monoclonal antibody conjugated with gold particules and directed against specific salmonella LPS core antigen. The immunochromatographic test is coated with a monoclonal immunoreagent specific for salmonella LPS antigens. Liquid sample and gold conjugate both migrate by capillarity and reach the first specific anti-salemonella monoclonal reagent. If salmonella is present in the sample, it is blocked and immunoreaction appears as a red-pink line. As sample still migrates, it reaches the second non specific anti-mouse IgG which gives rise to a second red-pink line. This rear line indicates that the chromatography has been developped without hindrance. It appears also with negative samples.

Features:

• Product Type: Colloidal Gold Rapid Test
• Detection Limit: High Sensitivity
• Application: Clinical/ Hospital/ Laboratory/ Home
• Package: 25/50/100 Tests/kit
• Shelf Life: 24 Months
• Type: Colloidal Gold
• Can be used as a Home Test or Self Test

Technical Parameters:

Precaution For Users:

1. For in-vitro diagnostic use only.

2. Handle all specimens as if they contain infectious agents. When the assay procedure is completed, dispose of specimens carefully after autoclaving for at least one hour. Alternatively, treat with a 0.5 or 1% solution of sodium hypochlorite for one hour before disposal.

3. Wear protective clothing (laboratory coats and disposable gloves) whenassaying samples.

4. Do not eat, drink or smoke in areas where specimens and kit reagents are handled.

Avoid contact between hands and eyes or nose during specimen collection and testing.

Support and Services:

The Colloidal Gold Rapid Test is a diagnostic tool designed for the qualitative detection in human fece samples. Technical support and services offered with this product include:

• Instructions for use and interpretation of results
• Technical assistance and troubleshooting
• Product training and education
• Product customization and development
• Quality control and assurance
• Regulatory compliance support