Shenzhen HongJie Water Technology Co., Ltd.
                                                                                                           
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13 Years
Since 2013
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Factory Price Ultrafiltration unit for Separation of biological products 500 lters per hour water filtration system

Price Negotiable
Price: negotiation
MOQ: 1set
Delivery Time: 1-7working days(depand on raw materials stocking)
Brand: HJW
Product Description

I.Overview
Ultrafiltration (UF) assumes the core tasks of concentration, purification, buffer replacement and removal of impurities in the separation of biological products, and is especially suitable for the fine treatment of large molecules of biologically active substances (e.g. proteins, vaccines, nucleic acids). UF system is the gold standard of biologics separation, and its irreplaceable core value in biopharmaceuticals lies in: activity preservation, precise separation, and compliance guarantee.


II.Key technology flow 
Typical route for downstream purification of monoclonal antibody: 
cell culture solution → centrifugation/microfiltration → Protein A chromatography → virus inactivation → **UF/DF (ultrafiltration dialysis)** → purified chromatography → preparation


Plasmid DNA purification process: 
bacteriophage lysis → alkaline extraction → ultrafiltration (100 kDa) → affinity chromatography → **tangential flow ultrafiltration (TFF)** → sterile filtration


III.Core Performance Parameters

Parameter Standard Requirement
Molecular Weight Cut - off 1/3 - 1/6 of the target molecular weight (e.g., 30 kDa for monoclonal antibodies)
Recovery Rate > 95% (for monoclonal antibodies)
HCP Residue < 100 ppm
Endotoxin Removal < 0.001 EU/mg
Shear Force Control Laminar shear force < 10 Pa·s


IV.Key Points for Equipment Selection

Membrane Module Type Applicable Scenarios
Hollow Fiber Large - volume Processing (>500L)
Flat Sheet Membrane Pack High - value - added Products (e.g., Gene Therapy)
Ceramic Membrane High - Viscosity/Particulate - containing Feed Liquid


V.Core Application Scenarios 
Monoclonal Antibodies 
Recombinant Proteins 
Viral Vectors 
Nucleic Acid Drugs 
Vaccines


VI.Here is a guideline for you to get a proper quotation
Tell us the raw water/source of water(tap water, well water, or sea water, etc)
Provide water analysis report(TDS , conductivity, or resistivity, etc)
Required production capacity( 5m³/H, 50m³/H,or 500m³/H, etc)
What's the pure water used for( industrial,Food and Beverage,or agriculture, etc )


Get in Touch

Have questions about our products or want to discuss a custom order? Our team is ready to help you.

Company Shenzhen HongJie Water Technology Co., Ltd.
Location Room 1105, Building 3, Xinsheng Green Valley Industrial Park, Xinsheng Community, Longgang Street, Longgang District, Shenzhen,China
Contact Person Cathy

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