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Cas 551-11-1 Synthetic Prostaglandin Dinoprost Prostaglandin F2a

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Price: Negotiable
MOQ: 1g
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Brand: Crene
Product Description

Cas 551-11-1 Synthetic Prostaglandin Dinoprost Prostaglandin F2a

 

Chemical Information
Product name:Dinoprost Prostaglandin F2a Purity:98% min
CAS NO:551-11-1 Solubility:Soluble in DMSO
Molecular Formula:C20H34O5 Package:Package according to customer requirements
Molecular Weight:354.48 Storage:Store at -20℃
Quality control
COA
Remarks
Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost (INN), is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
In domestic mammals, it is produced by the uterus when stimulated by oxytocin, in the event that there has been no implantation during the follicular phase. It acts on the corpus luteum to cause luteolysis, forming a corpus albicans and stopping the production of progesterone. Action of PGF2α is dependent on the number of receptors on the corpus luteum membrane.
The PGF2α isoform 8-iso-PGF2α was found in significantly increased amounts in patients with endometriosis, thus being a potential causative link in endometriosis-associated oxidative stress.
 
 
 

Related Prodcuts: (+)-Cloprostenol; Cloprostenol; Misoprostol; Carboprost; Tafluprost; Dinoprostone; Trometamol; Alprostadil; Iloprost; Limaprost; Bimatoprost; Latanoprost; Lubiprostone; 15-keto Travoprost; 15S-Travoprost; 5,6-trans Travoprost; Fluprostenol Travoprost acid

References

[1]. Sharma I, et al. Role of 8-iso-prostaglandin F2alpha and 25-hydroxycholesterol in the pathophysiology of endometriosis. Fertil Steril. 2010 Jun;94(1):63-70.

[2]. Coulthard G, et al. Stereocontrolled organocatalytic synthesis of prostaglandin PGF2α in seven steps. Nature. 2012 Sep 13;489(7415):278-81.

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