Etelcalcetide cas 1262780-97-1

Etelcalcetide, also known as AMG 416 and KAI-4169, is a D-amino peptide calcimimetic undergoing clinical evaluation for the treatment of secondary hyperparathyroidism for patients with chronic kidney disease (CKD) on hemodialysis. Etelcalcetide is administered intravenously at the end of each dialysis session. It functions by binding to and activating the calcium-sensing receptor (CaSR) in the parathyroid gland as an allosteric activator, resulting in PTH reduction and suppression. Elevated PTH is often observe in patients with CKD.

Related Prodcuts:

Dynorphin A (1-13); Deslorelin; Gonadorelin; Gonadorelin acetate; Sermorelin; Sermorelin Acetate; DSIP; Lixisenatide; Angiotensin acetate; Epithalone; Buserelin; Cilengitide; Cilengitide trifluoroacetate; Tesamorelin; Selank; ACTH (1-39) Seractide; Ipamorelin

[1]. Block GA, et al. Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial. JAMA. 2017 Jan 10;317(2):156-164.