Active Pharmaceutical Ingredient

Chemical Information Product name:PR-619 Purity:98% min CAS NO:2645-32-1 Solubility:DMSO : ≥ 21 mg/mL (94.05 mM) Molecular Formula:C7H5N5S2 Package:Package according to customer requirements. Molecular Weight:223.278 Storage:Store at -20℃ Quality control COA Remarks PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM in a cell-free assay. PR-619 is a cell-permeable pyridinamine class broad-spectrum DUB inhibitor whose

Chemical Information Product name:calcipotriol Purity:98% min CAS NO:112965-21-6 Solubility:DMSO : ≥ 100 mg/mL (242.37 mM) Molecular Formula:C27H40O3 Package:Package according to customer requirements Molecular Weight:412.605 Storage:Store at -20℃ Remarks Calcipotriol, a synthetic derivative of calcitriol or Vitamin D, is used in the treatment of psoriasis and marketed under the trade name Dovonex. It has comparable affinity with calcitriol (Vit. D) for the Vitamin D receptor

Chemical Information Product name:CYC-116 Purity:98% min CAS NO:693228-63-6 Solubility:DMSO : < 1 mg/mL Molecular Formula:C18H20N6OS Package:Package according to customer requirements Molecular Weight:368.456 Storage:Store at -20℃ Remarks CYC116 is an orally bioavailable small molecule multi-kinase inhibitor with antineoplastic activity. Aurora kinase/VEGFR 2 inhibitor CYC116 inhibits Aurora kinases A and B and vascular endothelial growth factor receptor 2 (VEGFR2), resulting

Chemical Information Product name:MK-8776 SCH900776 Purity:98% min CAS NO:891494-63-6 Solubility:DMSO : ≥ 100 mg/mL (265.78 mM) Molecular Formula:C15H18BrN7 Package:Package according to customer requirements Molecular Weight:376.254 Storage:Store at -20℃ Remarks SCH900776, also known as MK-8776. is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities. Chk1 inhibitor SCH 900776 specifically binds to and

Chemical Information Product name:Aleglitazar Purity:98% min CAS NO:475479-34-6 Solubility:DMSO : ≥ 50 mg/mL (114.28 mM); H2O : < 0.1 mg/mL Molecular Formula:C24H23NO5S Package:Package according to customer requirements Molecular Weight:437.508 Storage:Store at -20℃ Remarks Aleglitazar, also known as RG-1439 or RO-0728804, is a peroxisome proliferator-activated receptor agonist (hence a PPAR modulator ) with affinity to PPARα and PPARγ, Aleglitazar improves Insulin Sensitivit

Chemical Information Product name:AMG 900 Purity:98% min CAS NO:945595-80-2 Solubility:DMSO : ≥ 50 mg/mL (99.29 mM) Molecular Formula:C28H21N7OS Package:Packaging according to customer requirements Molecular Weight:503.578 Storage:Store at -20℃ Remarks AMG 900 is a small-molecule inhibitor of Aurora kinases A, B and C with potential antineoplastic activity. Aurora kinase inhibitor AMG 900 selectively binds to and inhibits the activities of Aurora kinases A, B and C, which may

Chemical Information Product name: 4-amino-3-chlorophenol Synonyms: 3-Chloro-4-aminophenol CAS No.: 17609-80-2 Molecular Formula: C6H6ClNO Molecular weight: 143.571 Technicel Data Appearance: light gray powder purity: 99.5%+ Solubility: Package: Package according to customer requirements Storage: Keep containers tightly closed. Store in a cool, dry area away from incompatible substances Shipping condition: Transport at room temperature or blue ice according to product storage

Chemical Information Product name:Inolitazone Purity:98% min CAS NO:223132-37-4 Solubility: Molecular Formula:C26H24N4O4S Package:Package according to customer requirements Molecular Weight:488.558 Storage:Store at -20℃ Remarks Inolitazone, also know as CS-7017, RS5444 and efatutazone , is an orally bioavailable PAPR-gamma inhibitor with potential antineoplastic activity. Inolitazone binds to and activates peroxisome proliferation-activated receptor gamma (PPAR-gamma), which

Chemical Information Product name:MLN0905 Purity:98% min CAS NO:1228960-69-7 Solubility:DMSO : ≥ 30 mg/mL (61.66 mM) Molecular Formula:C24H25F3N6S Package:Package according to customer requirements Molecular Weight:486.556 Storage:Store at -20℃ Remarks MLN0905 is a potent, selective small-molecule PLK1 inhibitor. MLN0905 inhibits cell proliferation in a broad range of human tumor cells including DLBCL cell lines. PLK1 inhibition leads to pharmacodynamic pHisH3 modulation and

Chemical Information Product name:Amrubicin Purity:98% min CAS NO:110267-81-7 Solubility:DMSO : ≥ 30 mg/mL (62.05 mM) Molecular Formula:C25H25NO9 Package:Package according to customer requirements Molecular Weight:483.467 Storage:Store at -20℃ Remarks Amrubicin, also known as SM-5887, is an anthracycline used in the treatment of lung cancer. Amrubicin intercalates into DNA and inhibits the activity of topoisomerase II, resulting in inhibition of DNA replication, and RNA and

Chemical Information Product name:Amrubicin HCl Purity:98% min CAS NO:110311-30-3 Solubility:Soluble in DMSO Molecular Formula:C25H26ClNO9 Package:Package according to customer requirements Molecular Weight:519.928 Storage:Store at -20℃ Remarks Amrubicin hydrochloride is the hydrochloride salt of a third-generation synthetic 9-amino-anthracycline with antineoplastic activity. Amrubicin intercalates into DNA and inhibits the activity of topoisomerase II, resulting in

Chemical Information Product name:BI 2536 Purity:98% min CAS NO:755038-02-9 Solubility:DMSO : ≥ 55.5 mg/mL (106.39 mM) Molecular Formula:C28H39N7O3 Package:Package according to customer requirements Molecular Weight:521.654 Storage:Store at -20℃ Remarks BI-2563 is a small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor

Chemical Information Product name:Scriptaid Purity:98% min CAS NO:287383-59-9 Solubility:DMSO : ≥ 150 mg/mL (459.63 mM) Molecular Formula:C18H18N2O4 Package:Package according to customer requirements Molecular Weight:326.347 Storage:Store at -20℃ Remarks Scriptaid, also known as GCK 1026, is a HDAC inhibitor. Scriptaid protects against traumatic brain injury via modulation of PTEN and AKT pathway. Scriptaid improves in vitro development and nuclear reprogramming of somatic

Chemical Information Product name:GSK-1070916A Purity:98% min CAS NO:942918-07-2 Solubility:DMSO : ≥ 26.5 mg/mL (52.20 mM) Molecular Formula:C30H33N7O Package:Package according to customer requirements Molecular Weight:507.629 Storage:Store at -20℃ Remarks GSK1070916, also known as NMI-900 or GSK-1070916A, is an ATP-competitive inhibitor of the serine/threonine kinases Aurora B and C with potential antineoplastic activity. Aurora B/C kinase inhibitor GSK1070916A binds to and

Chemical Information Product name:Moxifloxacin HCL Purity:98% min CAS NO:186826-86-8 Solubility:DMSO : ≥ 31 mg/mL (70.79 mM) Molecular Formula:C21H25ClFN3O4 Package:Package according to customer requirements Molecular Weight:437.892 Storage:Store at -20℃ Quality control COA Remarks Moxifloxacin is a fourth-generation synthetic fluoroquinolone antibacterial agent. Its antibacterial spectrum includes enteric Gram-(−) rods (Escherichia coli, Proteus species, Klebsiella species),

Chemical Information Product name:Entinostat (MS-275) Purity:98% min CAS NO:209783-80-2 Solubility:DMSO : ≥ 300 mg/mL (797.00 mM) Molecular Formula:C21H20N4O3 Package:Package according to customer requirements Molecular Weight:376.409 Storage:Store at -20℃ Remarks Entinostat, also known as MS-275 or SNDX-275, is a potent HDAC inhibitor with potential antineoplastic activity. Entinostat binds to and inhibits histone deacetylase, an enzyme that regulates chromatin structure and

Chemical Information Product name:Tenovin-1 Purity:98% min CAS NO:380315-80-0 Solubility:DMSO : 33.33 mg/mL (90.21 mM) Molecular Formula:C20H23N3O2S Package:Package according to customer requirements Molecular Weight:369.481 Storage:Store at -20℃ Remarks Tenovin-1 is a p53 activator and elevates the amount of p53 protein within 2 hr of treatment. Tenovin-1 treatment does not alter p53 mRNA levels. Tenovin-1 (10μM) protects p53 from mdm2-mediated degradation with little effect

Chemical Information Product name:ED-71 Eldecalcitol Purity:99% min CAS NO:104121-92-8 Solubility:Soluble in DMSO Molecular Formula:C30H50O5 Package:Package according to customer requirements Molecular Weight:490.715 Storage:Store at -20℃ Remarks Eldecalcitol is a drug used in Japan for the treatment of osteoporosis. It is an analog of vitamin D. Eldecalcitol is an orally administered drug to patients, which binds to vitamin D receptors and binding protein for the goal of

Chemical Information Product name:Calcifediol monohydrate Purity:98% min CAS NO:63283-36-3 Solubility:DMSO : ≥ 100 mg/mL (238.86 mM) Molecular Formula:C27H46O3 Package:Package according to customer requirements Molecular Weight:418.652 Storage:Store at -20℃ Quality control COA Remarks Calcifediol is a prehormone that is produced in the liver. Physicians worldwide measure this metabolite to determine a patient's vitamin D status. The blood concentration of calcifediol is

Chemical Information Product name:Paricalcitol Purity:98% min CAS NO:131918-61-1 Solubility:DMSO : 100 mg/mL (240.02 mM); H2O : < 0.1 mg/mL Molecular Formula:C27H44O3 Package:Package according to customer requirements Molecular Weight:416.636 Storage:Store at -20℃ Remarks Paricalcitol, marketed by Abbott Laboratories under the trade name Zemplar, is a drug used for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure. It is an