CID2858522 cas 758679-97-9

Name: CID2858522 cas 758679-97-9
Brand: Taizhou Crene Biotechnology Co., Ltd.

Price Negotiable

Price: Negotiable

MOQ: 1g

Delivery Time: Negotiable

Brand: Crene

Product Description

Chemical Information

Product name:CID2858522	Purity:98% min
CAS NO:758679-97-9	Solubility:10 mM in DMSO
Molecular Formula:C₂₈H₃₉N₃O₃	Package:Package according to customer requirements
Molecular Weight:465.628	Storage:Store at -20℃

Remarks

CID2858522, also known as ML029, is a potent and selective inhibitor of NF-κB Activation (C50 value of 0.07 μM). CID2858522 specifically inhibits NF-kB activation downstream of protein kinsase C (PKC). CID2858522 may be useful to researchers working in immunology, autoimmune diseases, transplantation and allograft rejection, lymphoid malignancies, immune signaling, and general signal transduction.

References

[1]. Okolotowicz KJ, et al. Selective benzimidazole inhibitors of the antigen receptor-mediated NF-kappaB activationpathway. Bioorg Med Chem. 2010 Mar 1;18(5):1918-24.

[2]. Shi R, et al. Chemical biology strategy reveals pathway-selective inhibitor of NF-kappaB activation induced by protein kinase C. ACS Chem Biol. 2010 Mar 19;5(3):287-99.