SSE15206 cas 1370046-40-4
| Product name:SSE15206 | Purity:98% min |
| CAS NO:1370046-40-4 | Solubility:DMSO : 150 mg/mL (403.82 mM) |
| Molecular Formula:C19H21N3O3S | Package:Package according to customer requirements |
| Molecular Weight:371.45 | Storage:Store at -20℃ |
SSE15206 is a microtubule depolymerizing agent that overcomes multidrug resistance. SSE15206 has potent antiproliferative activities in cancer cell lines of different origins and overcomes resistance to microtubule-targeting agents. Treatment of cells with SSE15206 causes aberrant mitosis resulting in G2/M arrest due to incomplete spindle formation, a phenotype often associated with drugs that interfere with microtubule dynamics. SSE15206 inhibits microtubule polymerization both in biochemical and cellular assays by binding to colchicine site in tubulin as shown by docking and competition studies.
Microtubule Associated Inhibitors Related Products:
Paclitaxel; Vincristine; Vincristine sulfate; Epothilone A; Fosbretabulin disodium; CW069; CK-636; Docetaxel; Docetaxel trihydrate; ABT-751; Nocodazole; Cabazitaxel; Albendazole; Mertansine; ELR510444; Vinorelbine Tartrate; Triclabendazole; Epothilone B
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