1A-116 cas 1430208-73-3

Name: 1A-116 cas 1430208-73-3
Brand: Taizhou Crene Biotechnology Co., Ltd.

Price Negotiable

Price: Negotiable

MOQ: 1g

Delivery Time: Negotiable

Brand: Crene

Product Description

Chemical Information

Product name:1A-116	Purity:99% min
CAS NO:1430208-73-3	Solubility:DMSO : 100 mg/mL (325.40 mM)
Molecular Formula:C₁₆H₁₆F₃N₃	Package:Package according to customer requirements
Molecular Weight:307.32	Storage:Store at -20℃

Remarks

1A-116 is a Rac1 inhibitor, with antitumoral and antimetastatic effects in several types of cancer, such as breast cancer. 1A-116 prevents Rac1-regulated processes involved in the primary tumorigenesis and metastastic processes .

Properties:

Boiling point: 357.5±52.0 °C(Predicted)

density: 1.22±0.1 g/cm3(Predicted)

pka: 9.78±0.10(Predicted)

Ras Related Products:

Sotorasib; Ketoconazole; (Rac)-Antineoplaston A10; CID-1067700; Kobe0065; Kobe-2602; ML141; Zoledronic acid; Lonafarnib; Adagrasib; Deltarasin; Salirasib; EHop-016; CCG-1423; ZCL-278; 6H05

References

[1]. Gonzalez N, et al. Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells. Cell Signal. 2017 Jan;30:154-161.

[2]. Cardama GA, et al. Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines. Anticancer Agents Med Chem. 2014;14(6):840-51.