SB2343 VS-5584 cas 1246560-33-7
| Product name:SB2343 VS-5584 | Purity:98% min |
| CAS NO:1246560-33-7 | Solubility:DMSO : 33.33 mg/mL (94.04 mM) |
| Molecular Formula:C21H14F2N6O2 | Package:Package according to customer requirements |
| Molecular Weight:420.372 | Storage:Store at -20℃ |
VS-5584, also known as SB2343, is a potent and selective inhibitor of both phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinase in the PI3K/mTOR signaling pathway, with potential antineoplastic activity. PI3K/mTOR kinase inhibitor VS-5584 inhibits mTOR kinase and all class I PI3K isoforms. Consequently, this disrupts phosphorylation of substrates downstream of PI3K and mTOR and may result in apoptosis and growth inhibition in susceptible tumor cells. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy.
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