Selective Inhibitor PD98059 Cas 167869-21-8
Selective Inhibitor PD98059 Cas 167869-21-8
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Chemical Information
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Product name:PD98059 |
Purity:98% min |
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CAS NO:167869-21-8 |
Solubility:DMSO: 16 mg/mL; H2O: < 0.01 mg/mL |
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Molecular Formula:C16H13NO3 |
Package:Package according to customer requirements |
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Molecular Weight:267.2790 |
Storage:Store at -20℃ |
Quality control
Remarks
PD98059 also known as PD-98059, is a potent and selective inhibitor of MAP kinase kinase (also known as MAPK/ERK kinase or MEK kinase). It mediates its inhibitory properties by binding to the ERK-specific MAP kinase MEK, therefore preventing phosphorylation of ERK1/2 (p44/p42 MAPK) by MEK1/2. MAPK ERK1/2 is involved in TLR-induced production of cytokines.
Related Products:
Alpelisib; Gedatolisib; AS-604850; CAY10505; AS-605240; Apitolisib; PIK-93; PIK-75 Hydrochloride; YM201636; ZSTK474; PI-103; GNE-493; MTX-211; AKTIV; Duvelisib; TGX-221; LY294002
References
[1].Reiners JJ Jr, et al. PD98059 is an equipotent antagonist of the aryl
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