Taizhou Crene Biotechnology Co., Ltd.
                                                                                                           
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Chemicals Organic Intermediate
China AZD5363 Capivasertib AKT Inhibitors for sale

AZD5363 Capivasertib AKT Inhibitors

Price Negotiable
Price: Negotiable
MOQ: 1g
Delivery Time: Negotiable
Brand: Crene
Product Description
Chemical Information
Product name:AZD5363 Capivasertib Purity:98% min
CAS NO:1143532-39-1 Solubility:DMSO : ≥ 21.5 mg/mL (50.13 mM)
Molecular Formula:C21H25ClN6O2 Package:Package according to customer requirements
Molecular Weight:428.915 Storage:Store at -20℃
Quality control
COA
Remarks

AZD5363, also known as Capivasertib, is an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity. AKT inhibitor AZD5363 binds to and inhibits all AKT isoforms. Inhibition of AKT prevents the phosphorylation of AKT substrates that mediate cellular processes, such as cell division, apoptosis, and glucose and fatty acid metabolism. A wide range of solid and hematological malignancies show dysregulated PI3K/AKT/mTOR signaling due to mutations in multiple signaling components.

 

 

Related Products:

MK-2206 2HCl; Ipatasertib; Triciribine; PHT-427; Perifosine; CCT128930; AT7867; AT13148; ONC-201; Akti-1/2; SC66; Miltefosine; GSK690693

References
[1]. Davies BR, et al. Preclinical pharmacology of AZD5363, an inhibitor of AKT: pharmacodynamics, antitumor activity, and correlation of monotherapy activity with genetic background. Mol Cancer Ther. 2012 Apr;11(4):873-87.
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Company Taizhou Crene Biotechnology Co., Ltd.
Location Add: Economic Developed Zone of Taizhou Zhejiang China.

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