YN-968D1 Apatinib Rivoceranib VEGFR Inhibitors Cas 811803-05-1
YN-968D1 Apatinib Rivoceranib VEGFR Inhibitors Cas 811803-05-1
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- Prostaglandins - Custom Synthesis - PARP Inhibitors - PI3K Inhibitors - FAK Inhibitors - AKT Inhibitors - C-Kit Inhibitors - VEGFR Inhibitors - c-Met Inhibitors - CDK Inhibitors - CYP17 Inhibitors - DNA/RNA Inhibitors - mTOR Inhibitors - SRC Inhibitors - Others
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Chemical Information
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Product name:YN-968D1 Apatinib |
Purity:98% min |
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CAS NO:811803-05-1 |
Solubility:DMSO: 79 mg/mL (198.75 mM) |
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Molecular Formula:C24H23N5O |
Package:Package according to customer requirements |
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Molecular Weight:397.472 |
Storage:Store at -20℃ |
Quality control
COA
Remarks
Apatinib, also known as Rivoceranib, is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. The free-base form is also known as Rivoceranib. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.
Related Prodcuts:
LY2874455; ZM-306416; ZM323881; Tyrphostin A9; Orantinib; Brivanib; Foretinib; SU5402; Semaxanib; SAR131675; Lucitanib; SKLB610; Altiratinib; SGI-7079; AZD2932
References
[1] Tian S, et al. Cancer Sci. 2011, 102(7):1374-80.
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