Dasabuvir Sodium RNA Synthesis Inhibitors
Chemical Information
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Product name:Dasabuvir Sodium |
Purity:98% min |
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CAS NO:1132940-11-4 |
Solubility:Soluble in DMSO |
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Molecular Formula:C26H26N3NaO5S |
Package:Package according to customer requirements |
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Molecular Weight:515.5570 |
Storage:Store at -20℃ |
Remarks
Dasabuvir(ABT-333) is a non-nucleoside inhibitor of NS5B viral RNA-dependent RNA polymerase that inhibits recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates with IC50 values between 2.2 and 10.7 nM. It is at least 7,000-fold selective for the inhibition of HCV genotype 1 polymerases over human/mammalian polymerases.
Related Prodcuts:
GW9662; TAS-103; TAS-103 dihydrochloride; BRD73954; PU-WS13; L189; SCR7; Ispinesib; Dasabuvir; Ellipticine; Rucaparib; Rucaparib phosphate; Rucaparib camsylate; CB-5083; Maytansinoid DM 1; Mirin; Dexrazoxane Hydrochloride; Nedaplatin; CAY10572
References
[1]. Kati W, et al. In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor. Antimicrob Agents Chemother. 2015 Mar;59(3):1505-11.
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