GSK2606414 cas 1337531-36-8
| Product name:GSK2606414 | Purity:98% min |
| CAS NO:1337531-36-8 | Solubility:DMSO : ≥ 31 mg/mL (68.67 mM) |
| Molecular Formula:C24H20F3N5O | Package:Package according to customer requirements. |
| Molecular Weight:451.444 | Storage:Store at -20℃ |
GSK2606414 is an orally available, potent, and selective PERK inhibitor. GSK2606414 inhibits PERK activation in cells and inhibits the growth of a human tumor xenograft in mice. Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states. Evidence that PERK is implicated in tumorigenesis and cancer cell survival stimulated our search for small molecule inhibitors.
Related Prodcuts:
Etoposide; Etoposide phosphate; ML-323; BMH-21; Nexturastat A; TMP269; ELR510444; Chidamide; Inauhzin; CW069; Purvalanol A; Purvalanol B; JW55; Tenovin-6; Tenovin-6 HCL; RKI-1447; AZD2461; Tasquinimod
Get in Touch
Have questions about our products or want to discuss a custom order? Our team is ready to help you.