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China Resminostat hydrochloride cas 1187075-34-8 for sale

Resminostat hydrochloride cas 1187075-34-8

Price Negotiable
Price: Negotiable
MOQ: 1g
Delivery Time: Negotiable
Brand: Crene
Product Description
Chemical Information
Product name:Resminostat hydrochloride Purity:98% min
CAS NO:1187075-34-8 Solubility:DMSO : ≥ 50 mg/mL (129.58 mM)
Molecular Formula:C16H20ClN3O4S Package:Package according to customer requirements
Molecular Weight:385.866 Storage:Store at -20℃
Remarks

Resminostat hydrochloride is a potent inhibitor of HDAC1, HDAC3 and HDAC6, with mean IC50 values of 42.5, 50.1, 71.8 nM, respectively, and shows less potent activities against HDAC8, with an IC50 of 877 nM.

 

 

 

 

Related Prodcuts:

Doxorubicin HCl; Epirubicin; Epirubicin HCl; Idarubicin HCl; Pirarubicin; Amrubicin; Amrubicin HCL; AMG 900; YK-4-279; AT-7519 HCL; Belinostat; Resminostat; Mizoribine; Daunorubicin hydrochloride

References

[1]. Mandl-Weber S, et al. The novel inhibitor of histone deacetylase resminostat (RAS2410) inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells. Br J Haematol. 2010 May;149(4):518-28.

[2]. Enzenhofer E, et al. Effect of the histone deacetylase inhibitor resminostat on head and neck squamous cell carcinoma cell lines. Head Neck. 2017 May;39(5):900-907.

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Company Taizhou Crene Biotechnology Co., Ltd.
Location Add: Economic Developed Zone of Taizhou Zhejiang China.

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