Gemcitabine HCL cas 122111-03-9
| Product name:Gemcitabine HCL | Purity:98% min |
| CAS NO:122111-03-9 | Solubility:H2O : ≥ 66.66 mg/mL (222.45 mM) |
| Molecular Formula:C9H12ClF2N3O4 | Package:Package according to customer requirements |
| Molecular Weight:299.659 | Storage:Store at -20℃ |
Gemcitabine hydrochloride is the hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis.
Related Prodcuts:
Cisplatin; Bleomycin Sulfate; Temozolomide; Carmustine; CX-5461; Fludarabine Phosphate; Nelarabine; Cladribine; Trifluridine; Daptomycin; Givinostat hydrochloride monohydrate
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