P005091 cas 882257-11-6
| Product name:P005091 | Purity:98% min |
| CAS NO:882257-11-6 | Solubility:DMSO : 50 mg/mL (143.59 mM) |
| Molecular Formula:C12H7Cl2NO3S2 | Package:Package according to customer requirements |
| Molecular Weight:348.225 | Storage:Store at -20℃ |
P005091 is a potent and selective inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 4.2 μ M). P005091 induces elevated p53 and apoptosis in cancer cell lines and displays antiangiogenic activity in vivo . The deubiquitylating enzyme USP7 (HAUSP) sits at a critical node regulating the activities of numerous proteins broadly characterized as tumor suppressors, DNA repair proteins, immune responders, viral proteins, and epigenetic modulators. Aberrant USP7 activity may promote oncogenesis and viral disease making it a compelling target for therapeutic intervention.
Related Prodcuts:
Talazoparib; Aleglitazar; Miriplatin; Scriptaid; Ceritinib; CGK733; Tacedinaline; PR-619; Gemcitabine; Gemcitabine HCL; Terbinafine hydrochloride; Mitomycin C; Clevudine; Givinostat hydrochloride monohydrate
Get in Touch
Have questions about our products or want to discuss a custom order? Our team is ready to help you.