Cas 23541-50-6 DNA Synthesis Inhibitors Daunorubicin Hydrochloride
Cas 23541-50-6 DNA Synthesis Inhibitors Daunorubicin Hydrochloride
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Chemical Information
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Product name:Daunorubicin hydrochloride |
Purity:98% min |
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CAS NO:23541-50-6 |
Solubility:DMSO125 mg/mL (221.64 mM) |
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Molecular Formula:C27H30ClNO10 |
Package:Package according to customer requirements |
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Molecular Weight:563.981 |
Storage:Store at -20℃ |
Quality control
COA
Remarks
Daunorubicin hydrochloride is the hydrochloride salt of an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis.
Related Prodcuts:
Doxorubicin HCl; Epirubicin; Epirubicin HCl; Idarubicin HCl; Pirarubicin; Amrubicin; Amrubicin HCL; AMG 900; YK-4-279; AT-7519 HCL; Belinostat; Resminostat; Resminostat hydrochloride; Mizoribine
References
[1].Lehmann M, et al. Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test. Environ Mol Mutagen. 2004;43(4):250-7.
[2].Svensson SP, et al. Melanin inhibits cytotoxic effects of Doxorubicin and Daunorubicin in MOLT 4 cells. Pigment Cell Res. 2003 Aug;16(4):351-4
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