Taizhou Crene Biotechnology Co., Ltd.
                                                                                                           
Verified Supplier
19 Years
Since 2007
Menu
Menu
Home
Products
Show All Products
Synthesis Inhibitors
PARP Inhibitors
PI3K Inhibitors
Synthetic Prostaglandin
Monoclonal Antibody
AKT Inhibitors
C Kit Inhibitors
VEGFR Inhibitors
C Met Inhibitors
CDK Inhibitors
CYP17 Inhibitors
RNA Synthesis Inhibitors
DNA Synthesis Inhibitors
MTOR Inhibitors
SRC Inhibitors
Active Pharmaceutical Ingredient
Custom Chemical Synthesis
Pharmaceutical Intermediates
About Us
Contact Us
China CYC-116 cas 693228-63-6 for sale

CYC-116 cas 693228-63-6

Price Negotiable
Price: Negotiable
MOQ: 1g
Delivery Time: Negotiable
Brand: Crene
Product Description
Chemical Information
Product name:CYC-116 Purity:98% min
CAS NO:693228-63-6 Solubility:DMSO : < 1 mg/mL
Molecular Formula:C18H20N6OS Package:Package according to customer requirements
Molecular Weight:368.456 Storage:Store at -20℃
Remarks

CYC116 is an orally bioavailable small molecule multi-kinase inhibitor with antineoplastic activity. Aurora kinase/VEGFR 2 inhibitor CYC116 inhibits Aurora kinases A and B and vascular endothelial growth factor receptor 2 (VEGFR2), resulting in disruption of the cell cycle, rapid cell death, and the inhibition of angiogenesis. Aurora kinases are serine/threonine protein kinases that are only expressed in actively dividing cells and are critical in division or mitosis. VEGFR2 is a receptor tyrosine kinase that appears to account for most of the mitogenic and chemotactic effects of vascular endothelial growth factor (VEGF) on adult endothelial cells.

 

 

 

Related Prodcuts:

Tenovin-1; CHR-6494; LDN-192960; Epothilone D; Cladribine; VX-680; BI 2536; GW843682X; MK-1775; Entinostat

References
[1]. Wang S, et al. Discovery of N-phenyl-4-(thiazol-5-yl)pyrimidin-2-amine aurora kinase inhibitors. J Med Chem. 2010 Jun 10;53(11):4367-78.
Similar Products
China FPH2 BRD-9424 cas 957485-64-2 for sale

FPH2 BRD-9424 cas 957485-64-2
China PR-619 cas 2645-32-1 for sale

PR-619 cas 2645-32-1
China (S)-3,4-DCPG cas 201730-11-2 for sale

(S)-3,4-DCPG cas 201730-11-2
China Epithalone cas 307297-39-8 for sale

Epithalone cas 307297-39-8
China Gonadorelin cas 33515-09-2 for sale

Gonadorelin cas 33515-09-2
China Etelcalcetide cas 1262780-97-1 for sale

Etelcalcetide cas 1262780-97-1
China Ticagrelor intermediate cas 274693-53-7 for sale

Ticagrelor intermediate cas 274693-53-7
China Calcitriol Intermediate cas 147125-14-2 for sale

Calcitriol Intermediate cas 147125-14-2
China 3-oxo-1,3-dihydroisobenzofuran-1-ylphosphonic acid cas 61260-15-9 for sale

3-oxo-1,3-dihydroisobenzofuran-1-ylphosphonic acid cas 61260-15-9
China calcipotriol cas 112965-21-6 for sale

calcipotriol cas 112965-21-6
China bimatoprost intermediates cas 1393740-68-5 for sale

bimatoprost intermediates cas 1393740-68-5
China RKI-1447 cas 1342278-01-6 for sale

RKI-1447 cas 1342278-01-6

Get in Touch

Have questions about our products or want to discuss a custom order? Our team is ready to help you.

Company Taizhou Crene Biotechnology Co., Ltd.
Location Add: Economic Developed Zone of Taizhou Zhejiang China.

Request A Quote

Please check your email address.
Your message must be at least 20 characters.