GW843682X cas 660868-91-7
Price:
Negotiable
MOQ:
1g
Delivery Time:
Negotiable
Brand:
Crene
Product Description
Chemical Information
| Product name:GW843682X | Purity:98% min |
| CAS NO:660868-91-7 | Solubility:DMSO : 33.33 mg/mL (69.81 mM) |
| Molecular Formula:C22H18F3N3O4S | Package:Package according to customer requirements |
| Molecular Weight:477.456 | Storage:Store at -20℃ |
Remarks
GW843682X is a selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively). GW843682X inhibited the proliferation and induced apoptosis of 5-8F cells in a dose-dependent manner (IC50=62.5-125nmol/L). GW843682X exhibited remarkable cytotoxic effects on nasopharyngeal carcinoma 5-8F cells by down-regulating IAP gene expression, suggesting that GW843682X may become a novel therapeutic agent for nasopharyngeal carcinoma.
Related Prodcuts:
Tenovin-1; CHR-6494; LDN-192960; Epothilone D; Cladribine; VX-680; BI 2536; CYC-116; MK-1775; Entinostat
References
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Company
Taizhou Crene Biotechnology Co., Ltd.
Location
Add: Economic Developed Zone of Taizhou Zhejiang China.